[1] Warmke J,Drysdale R,Ganetzky B.A distinct potassium channel polypeptide encoded by the Drosophila eag locus[J].Science,1991,252(5012):1560-1562.DOI:10.1126/science.1840699 [2] Dolderer JH,Schuldes H,Bockhom H,et al. HERGl gene expression as a specific tumor marker in colorectal tissues[J].EJSO,2010,36(1):72-77.DOI:doi:10.1016/j.ejso.2009.05.009. [3] Pillozzi S,Brizzi MF,Bemabei PA,et al. VEGFR-l (FLT-l),piintegrin,and HERGK+ channel for a macromolecular signaling complex in acute myeloid leukemia;role in cell migration and clinical outcome[J].Blood,2007,110(4):1238-1250.DOI:10.1182/blood-2006-02-003772. [4] Li H,Liu L,Guo T,et al. Expression and fuactional role of HERGl,K+ channels in leukemic cells and leukemicstem cells[J].J Huazhong Uni Sci Technol,2007,27(3):257-260.DOI:10.1007/s11596-007-0310-2 [5] Chen X, Mao C, Wu R, et al. Use of the combination of the preoperative platelet-to-lymphocyte ratio and tumor characteristics to predict peritoneal metastasis in patients with gastric cancer[J].PloS one, 2017, 12(4):e0175074.DOI:10.1371/journal.pone.0175074. [6] Cui Y, Li Q, Li H, et al.asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through iQgaP1 modulating the egFr/JnK/erK signaling pathway[J].OncoTargets and therapy, 2017, 10:627.DOI:10.2147/OTT.S125579. [7] Borowiec AS,Hague F,Harir N,et al. IGF-1 activates hEAG K+channels through an Akt-dependent signaling pathway in breast cancer cells:role in cell proliferation[J].J Cell Physiol,2007,212(3):690-701.DOI:10.1002/jcp.21065 [8] 陈杰,于双妮,马怡晖,等.人胰腺癌中miRNA的差异表达及部分功能研究[J].中华病理学杂志,2011,40(12):860-861.DOI:10.3760/cma.j.issn.0529-5807.2011.12.019. Chen J,Yu SN,Ma YH,et al. Differential expression of miRNA in human pancreatic carcinoma and its partial function[J].Chin J Pathol,2011,40(12):860-861.DOI:10.3760/cma.j.issn.0529-5807.2011.12.019. [9] 汪霄.康莱特对晚期乳腺癌患者血清miRNA-21的影响研究[J].中国现代医生,2016,54(3):70-72,76. Wang X.Study on the effect of Kanglaite Injection on serum miRNA-21 in patients with advanced breast cancer[J].Chin Mode Doctor,2016,54(3):70-72,76. [10] 戴勇,穆柏银,唐亚平.miR-711对胃癌MGC-803细胞侵袭转移及上皮间质转化的影响[J].肿瘤防治研究,2016,43(3):201-206.DOI:10.3971/j.issn.1000-8578.2016.03.007. Dai Y,Mu BG,Tang YP.Effects of miR-711 on invasion and metastasis of gastric cancer MGC-803 cells and epithelial mesenchymal transition[J].Cancer Prevent Res,2016,43(3):201-206.DOI:10.3971/j.issn.1000-8578.2016.03.007. [11] 陈志铭,张岩,纪妹.微小RNA-125b过表达对肿瘤顺铂耐药细胞的影响[J].中华实验外科杂志,2016,33(3):834-835.DOI:10.3760/cma.j.issn.1001-9030.2016.03.087. Chen ZM,Zhang Y,Ji S.Effects of overexpression of RNA-125b on cisplatin resistance in tumor cells[J].Chin J Exper Surg,2016,33(3):834-835.DOI:10.3760/cma.j.issn.1001-9030.2016.03.087. [12] Yu S,Lu Z C,Meng Y,et al.miRNA-96 suppresses KRAS and functions as a tumor suppressor gene in pancreatic cancer.[J].Cancer Research,2010,70(14):6015-6025.DOI:10.1158/0008-5472.CAN-09-4531. [13] Wang H,Zhang Y,Cao L,et al. HERG K+ channel,a regulator of tumor cell apoptosis and proliferation.[J].Cancer Research,2002,62(17):4843-4848. [14] Shao X D,Wu K C,Guo X Z,et al. Expression and significance of HERG protein in gastric cancer[J].Cancer Biology& Therapy,2008,7(1):45-50. [15] Afrasiabi E,Hietamki M,Viitanen T,et al. Expression and significance of HERG (KCNH2) potassium channels in the regulation of MDA-MB-435S melanoma cell proliferation and migration[J].Cellular Signalling,2010,22(1):57-64.DOI:10.1016/j.cellsig.2009.09.010. [16] 冯锦.miR-96调控HERG1基因抑制胰腺癌增殖转移的实验研究[D].南京医科大学,2013. Feng J.Inhibitory effect of miR-96 on the proliferation and metastasis of pancreatic cancer by HERG1 gene[D].Nanjing Medical University,2013.
2017, Vol. 26 
