[an error occurred while processing this directive]|[an error occurred while processing this directive]
用KV-CBCT探讨两种下肢固定方法对直肠癌IMRT摆位误差影响
孟怡然,许青,章真,龚敏,任珺
200032 上海,复旦大学上海医学院肿瘤学系复旦大学肿瘤医学院放疗科
Influence of lower limb movements on setup errors in radiotherapy for rectal cancer using kilovoltage cone-beam CT (KV-CBCT)
Meng Yiran,Xu Qing,Zhang Zhen,Gong Min,Ren Jun
Department of Radiation Oncology,Cancer Hospital of Fudan University;Department of Oncology,Shanghai Medical College of Fudan University;Shanghai 200032,China
Abstract:Objective To investigate the influence of fixation of both lower limbs with negative pressure vacuum cushion and fixation of both ankles with self-made foam mat on setup errors in radiotherapy for rectal cancer. Methods A total of 12 patients with rectal cancer were enrolled in 2014 and randomly divided into group A (using negative pressure vacuum cushion) and group B (using self-made foam mat).An offline registration analysis was performed for the images of 108 times (A,B group of 54 times) of kilovoltage cone-beam CT (CBCT) before and after treatment. Grey scale translation error registration was used, and the results of registration were analyzed. The setup errors in x-axis (left-right direction), y-axis (cranial-caudal direction), and z-axis (anterior-posterior direction) were compared between the two groups. Results There was no significant difference in the absolute setup error in the y-axis between the two groups (2.13±0.64 mm vs.2.61±1.17 mm,P=0.399), while group A showed significantly lower absolute setup errors in the x-axis and z-axis than group B (x-axis:1.51±0.28 mm vs. 2.70±1.05 mm,P=0.039;with an error rate of 7.41% vs. 42.59%;z-axis:1.10±0.29 mm vs. 2.37±0.71 mm,P=0.002;with an error rate of 1.85% vs. 35.19%). Conclusions In the radiotherapy positioning for rectal cancer, fixation of both lower limbs with negative pressure vacuum cushion effectively avoids the translation and rotation of both lower limbs, reduces absolute setup errors, and has higher accuracy than fixation of both ankles with self-made foam mat.
Meng Yiran,Xu Qing,Zhang Zhen et al. Influence of lower limb movements on setup errors in radiotherapy for rectal cancer using kilovoltage cone-beam CT (KV-CBCT)[J]. Chinese Journal of Radiation Oncology, 2016, 25(9): 955-957.
[1] 何昱,卜路懿,严丹方.两种不同固定方法对于直肠癌放疗摆位误差的比较[J].医药前沿,2013,(5):87-88. He Y,Bo LY,Yan DF Two different fixation methods for colorectal cancer radiotherapy beam position error comparison[J].Med Front,2013,(5):87-88. [2] 潘建基,潘才住,陈传本,等.摆位系统误差对鼻咽癌调强放疗剂量的影响[J].中华放射肿瘤学杂志,2007,16(5):394-396.DOI:10.3760/j.issn:1004-4221.2007.05.018. Pan JJ,Pan CZH,Chen CHB,et al. Effect of position system errors on dose of IMRT for nasopharyngeal carcinoma[J].Chin J Radiat Oncol,2007,16(5):394-396.DOI:10.3760/j.issn:1004-4221.2007.05.018. [3] 李兴德,赵瑾,翟福山,等.自制双下肢辅助固定装置在盆腔肿瘤放疗中的应用分析[J].中华放射肿瘤学杂志,2015,24(4):371-372.DOI:10.3760/cma.j.issn.1004-4221.2015.04.004. Li XD,Zhao J,Zhai FSH,et al. Analysis of the application of self-made double lower limb auxiliary fixation device in the radiotherapy of pelvic tumors[J].Chin J Radit Oncol,2015,24(4):371-372.DOI:10.3760/cma.j.issn.1004-4221.2015.04.004. [4] 胡逸民.治疗体位及体位固定技术[A]//殷慰伯,余子豪,徐国镇,等.肿瘤放疗学[M].4版.北京:中国协和医科大学出版社,2008:95. Hu YM.Treatment of body position and posture fixation[A]//Yin WB,Yu ZH,Xu GZH,et al. Radiation Oncology[M].4 ed. Beijing:Peking Union Medical College press,2008:95. [5] 惠周光,王群,韩伟,等.食管癌放疗两种不同固定体位对摆位误差的影响[J].中华放射肿瘤学杂志,2014,23(4):336-339.DOI:10.3760/cma.j.issn.1004-4221.2014.04.015. Hui ZHG,Wang Q,Han W,et al. Comparation of set-up errors between two different body positions in precision radiotherapy for esophageal cancer[J].Chin J Radiat Oncol,2014,23(4):336-339.DOI:10.3760/cma.j.issn.1004-4221. 2014.04.015. [6] 钟亚华,周云峰,谢丛华,等.真空成型袋在盆腔野放疗中的价值[J].中华放射肿瘤学杂志,2002,11(4):240-242.DOI:10.3760/j.issn:1004-4221.2002.04.008. Zhong YH,Zhou YF,Xie CH,et al. Value of vacuum bag and set-up errors of two different immobilization techniques during pelvic irradiation[J].Chin J Radiat Oncol,2002,11(4):240-242.DOI:10.3760/j.issn:1004-4221.2002.04.008. [7] Catton C,Lebar L,Warde P,et al. Improvement in total positioning error for lateral prostate fields suing a soft immobilization device[J].Radiother Oncol,1997,44(3):265-270.DOI:10.1016/S0167-8140(97)00061-3. [8] Mubata CD,Bidmead AM,Ellingham LM,et al. Portal imaging protocol for radical dose-escalated radiotherapy treatment of prostate cancer[J].Int J Radiat Oncol Biol Phys,1998,40(1):221-231.DOI:10.1016/S0360-3016(97)00551-8. [9] Bel A,Vos PH,Rodringus PTR,et al. High-precision prostate cancer irradiation by clinical application of an off-line patient set-up verification procedure using portal imaging[J].Int J Radiat Oncol Biol Phys,1996,35(2):321-332.DOI:10.1016/0360-3016(95)02395-X. [10] 徐坚,邹云云,李瑞峰,等.改进激光标志对真空垫固定体位食管癌放疗摆位误差和摆位时间的影响[J].现代肿瘤医学,2013,21(6):1353-1355.DOI:10.3969/j.issn.1672-4992. 2013.06.58. Xu J,Zou YY,Li RF,et al. Affect of set-up error and set-up time with vacuum bag immobilization by improving the laser mark in radiotherapy for esophageal cancer[J].Mod Oncol,2013,21(6):1353-1355.DOI:10.3969/j.issn.1672-4992.2013.06.58.