[1] Folstein MF,Folstein SE,McHugh PR. “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res,1975,12:189-198. [2] Meyers CA,Hess KR,Yung WK,et al. Cognitive function as a predictor of survival in patients with recurrent malignant glioma. J Clin Oncol,2000,18:646-650. [3] Woo E,Lam K,Yu YL,et al. Cerebral radionecrosis: is surgery necessary? J Neuro Neurosur Psychiatry,1987,50:1407-1414. [4] Lee PWH,Hung BKM,Woo EKW,et al. Effects of radiation therapy on neuropsychological functioning in patients with nasopharyngeal carcinoma. J Neurol Neurosurg Psychiatry,1989,52:488-492. [5] Hua MS,Chen ST,Tang LM,et al. Neuropsychological function in patients with nasopharyngeal carcinoma after radiotherapy. J Clin Exp Neuropsychol,1998,20:684-693. [6] Cheung MC,Chan AS,Law SC,et al. Cognitive function of patients with nasopharyngeal carcinoma with and without temporal lobe radionecrosis. Arch Neurology,2000,57:1347-1352. [7] 欧广飞,蔡伟明.鼻咽癌放疗后长期生存病人的记忆力减退与脑损伤相关性的研究.中华放射肿瘤学杂志,1999,8:77-79. [8] 陈文,王金华,凌翔.鼻咽癌患者放疗前后记忆的变化.上海精神医学,2000,12:206-207. [9] 贺秋冬,杨立,卢原,等.放疗对鼻咽癌病人智力和记忆的影响.中国实用医药,2007,2:14-16. [10] Wolden SL,Chen WC,Pfister DG,et al. Intensity-modulated radiation therapy(IMRT) for nasopharynx cancer: update of the Memorial Sloan-Kettering experience. Int J Radiat Oncol Biol Phys,2006,64:57-62. [11] Lee AW,Ng WT,Hung WM. Major late toxicities after conformal radiotherapy for nasopharyngeal carcinoma-patient-and treatment-related risk factors. Int J Radiat Oncol Biol Phys,2009,73:1121-1128. [12] Hsiao KY,Yeh SA,Chang CC. Cognitive function before and after intensity-modulated radiation therapy in patients with nasopharyngeal carcinoma: a prospective study. Int J Radiat Oncol Biol Phys,2010,77:722-726. [13] Scoville WB,Milner B. Loss of recent memory after bilateral hippocampal lesions. J Neurol Neurosurg Psychiatry,1957,20:11-21. [14] Shors TJ,Miesegaes G,Beylin A,et al. Neurogenesis in the adult is involved in the formation of trace memories. Nature,2001,410:372-376. [15] Cameron HA,Gould E. Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neuroscience,1994,61:203-209. [16] Lemaire V,Koehl M,Le Moal M,et al. Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus. Proc Natl Acad Sci USA,2000,97:11032-11037. [17] Mizumatsu S,Monje ML,Morhardt DR,et al. Extreme sensitivity of adult neurogenesis to low doses of X-irradiation. Cancer Res,2003,63:4021-4027. [18] Raber J,Rola R,LeFevour A,et al. Radiation-induced cognitive impairments are associated with changes in indicators of hippocampal neurogenesis. Radiat Res,2004,162:39-47. [19] Nagai R,Tsunoda S,Hori Y,et al. Selective vulnerability to radiation in the hippocampal dentate granule cells. Surg Neurol,2000,53:503-506. [20] Monje ML,Toda H,Palmer TD. Inflammatory blockade restores adult hippocampal neurogenesis. Science,2003,302:1760-1765. [21] Mahajan A,Dong L,Prabhu S,et al. Application of deformable image registration to hippocampal doses and neurocognitive outcomes. Soc Neuro-Oncol,2007,9:538. [22] 吴晨彬,吴君心,徐鹭英,等.鼻咽癌调强放疗对海马结构的剂量影响分析.中华放射医学与防护杂志,2012,32:297-300. [23] A Phase Ⅱ Trial of Hippocampal Avoidance During Whole Brain Radiotherapy for Brain Metastases-RTOG CCOP Study[2012-08-10].http://www.rtog.org/ClinicalTrials/ProtocolTable/StudyDetails.aspx?study=0933. [24] Gondi V,Tomé WA,Mehta MP. Why avoid the hippocampus? A comprehensive review. Radiother Oncol,2010,97:370-376.
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