Abstract: 【Purpose/significance】With the imminent novel coronavirus pneumonia (COVID-19) and the world mocking conference in

early 2020,the reform of education paradigm is imminent.In the post epidemic era,changing the existing educational organization mode, service mode and teaching mode will help to build a new educational form and a new talent training paradigm in the intelligent era.【Method/process】By combing the relevant literature of "mixed teaching" and analyzing the advantages and disadvantages of online and offline teaching modes,this paper constructs a "double line mixed integration and symbiosis" teaching mode of medical informa-tion literacy education based on SECI knowledge transformation model from the perspective of knowledge transformation cycle【. Result/conclusion】This study will help to reconstruct and transform the teaching process of Internet plus medical information literacy educa-tion in the post epidemic era,improve teaching experience and enhance the ability of digital teaching service

【. Innovation/limitation】It breaks the limitations of traditional offline teaching and online teaching, uses technical means to change the traditional classroom teaching mode,makes the teaching reform in the post epidemic era from emergency to normal,reduces the difference between learning expectation and learning experience,and improves the efficiency of education and teaching.However,the wide promotion is also subject to the influence of multiple factors such as teaching system,technical conditions,discipline types and teachers.