AbstractObjective To evaluate the effect of the discrepancy of the dose calculation results of different algorithms upon the CyberKnife lung tumor treatment plan,and assess the impact of tumor volume and location on the dose calculation results. Methods Thirty-two cases of lung tumors were treated with MultiPlan 5.2.1 planning system of CyberKnife VSI.Ray Tracing and Monte Carlo algorithms were adopted to calculate the dose distribution,and then the calculation results were statistically compared between two algorithms. Results For the enrolled cases,the calculation results of these two algorithms demonstrated that the deviation range of prescription dose coverage of planning target volume (PTV),conformal index,new conformal index and uniformity index were 0.93%~68.80%,0.87%~17.21%,-212.38%~8.27% and 0%~15.17%,respectively. Conclusions In the CyberKnife treatment of lung tumors,the volume and location of tumors exert significant impact on the discrepancies of the dose calculation results of different algorithms. The smaller tumor volume and longer beam heterogeneity path are likely to generate a greater discrepancy. It is recommended to adopt or refer to the calculation results of Monte Carlo algorithm to deliver corresponding treatment.
Fund:National Key Research and Development Plan for Digital Diagnostic Equipment Research and Development (2016YFC0106701)
Corresponding Authors:
Li Qin,Email:675181445@qq.com
Cite this article:
Yang Jing,Liu Hongyuan,Cao Ting et al. Effect of the discrepancy of the dose calculation results of different algorithms on CyberKnife lung tumor treatment plan[J]. Chinese Journal of Radiation Oncology, 2018, 27(12): 1083-1087.
Yang Jing,Liu Hongyuan,Cao Ting et al. Effect of the discrepancy of the dose calculation results of different algorithms on CyberKnife lung tumor treatment plan[J]. Chinese Journal of Radiation Oncology, 2018, 27(12): 1083-1087.
[1] Onishi H,Shirato H,Nagata Y,et al. Stereotactic body radiotherapy (SBRT) for operable stage Ⅰ non–small-cell lung cancer:can SBRT be comparable to surgery?[J].Int J Radiat Oncol Biol Phys,2011,81(5):1352-1358.DOI:10.1016/j.ijrobp.2009.07.1751. [2] Wilcox EE,Daskalov GM,Lincoln H,et al. Comparison of planned dose distributions calculated by Monte Carlo and Ray-Trace algorithms for the treatment of lung tumors with cyberknife:a preliminary study in 33 patients[J].Int J Radiat Oncol,2010,77(1):277-284.DOI:10.1016/j.ijrobp.2009.08.001. [3] Solberg TD,Demarco JJ,Holly FE,et al. Monte Carlo treatment planning for stereotactic radiosurgery[J].Radiot Oncol J Eur Soc Ther Radiol Oncol,1998,49(1):73-84.DOI:10.1016/S0167-8140(98)00065-6. [4] Wilcox EE,Daskalov GM.Accuracy of dose measurements and calculations within and beyond heterogeneous tissues for 6 MV photon fields smaller than 4 cm produced by Cyberknife[J].Med Phys,2008,35(6):2259-2266.DOI:10.1118/1.2912179. [5] Koksal C,Akbas U,Okutan M,et al. Comparison of dose distributions calculated by the cyberknife Monte Carlo and ray tracing algorithms for lung tumors:a phantom study[C].Proceedings of the te European physical journal conferences,2015,03003,1-3.DOI:10.1051/epjconf/201510003003. [6] Araki F.Monte Carlo study of a Cyberknife stereotactic radiosurgery system[J].Med Phys,2006,33(8):2955-2963.DOI:10.1118/1.2219774. [7] Galonske K,Thiele M,Ernst I,et al. Comparison of treatment plans calculated by Ray Tracing and Monte Carlo algorithms for head and thorax radiotherapy with Cyberknife[J].Curr Direc Biomed Eng,2017,3(2):647-650.DOI:10.1515/cdbme-2017-0136. [8] Okoye CC,Patel RB,Hasan S,et al. Comparison of Ray Tracing and Monte Carlo calculation algorithms for thoracic spine lesions treated with CyberKnife-Based stereotactic body radiation therapy[J].Technol Cancer Res,2016,15(1):1-7.DOI:10.1177/1533034614568026. [9] Wu VWC,Kwok-Wah T,Shun-Ming T.Evaluation of the influence of tumor location and size on the difference of dose calculation between Ray Tracing algorithm and Fast Monte Carlo algorithm in stereotactic body radiotherapy of non-small cell lung cancer using CyberKnife[J].J Appl Clin Med Phys,2013,14(5):68-78.Doi:10.1120/jacmp.v14i5.4280. [10] 曹洋森,于春山,张火俊,等.射波刀蒙特卡罗与射线追踪算法在肺部肿瘤中的剂量学比较[J].医疗卫生装备,2016,37(4):97-99.DOI:10.7687/j.issn1003-8868.2016.04.097. Cao YS,Yu CS,Zhang HJ,et al. Comparison of dose distributions calculated by Monte Carlo and ray tracing algorithms for treatment of lung tumors with CyberKnife[J].Chin Med Equ J,2016,37(4):97-99.DOI:10.7687/j.issn 1003-8868.2016.04.097. [11] 朴俊杰,徐寿平,巩汉顺,等.CyberKnife系统技术评估和临床应用评价[J].医疗卫生装备,2016,37(3):114-117.DOI:10.7687/ j.issn1003-8868.2016.03.114. Piao JJ,Xu SP,Gong HS,et al. Assessment of technology and clinical application of CyberKnife system[J].Chin Med Equ J,2016,37(3):114-117.DOI:10.7687/J.ISSN1003-8868.2016.03.114. [12] 李玉,徐慧军,张素静.立体定向放疗计划中蒙特卡罗与射线追踪算法剂量计算结果的比较[J].中华放射医学与防护杂志,2012,32(6),629-630.DOI:10.3760/cma.j.issn.0254-5098.2012.06.017. Li Y,Xu HJ,Zhang SJ.Comparison of the dose calculation results of Monte Carlo and Ray Tracing algorithm in stereotactic body radiotherapy[J].Chin J Radiol Med Prot,2012,32(6),629-630.DOI:10.3760/cma.j.issn.0254-5098.2012.06.017.
2018, Vol. 27 
