调强放疗计划设计参数对剂量验证结果影响的初步研究

doi:10.3760/cma.j.issn.1004-4221.2018.10.013

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Abstract

Objective To analyze the relationship between planning factors of intensity-modulated radiation therapy (IMRT) and gamma index and investigate the effect of each parameter upon the γ passing rate of IMRT. Methods Gamma analysis was performed using 3%/3 mm acceptance criteria for 457 IMRT beams with different planning factors. During multi-factor ANOVA analysis of planning factors and gamma passing rate,the control variables primarily included the minimum segment area,minimum number of monitor unit (MU),number of segment,segment conversation,and the spatial resolution in the measured dose distribution. Results The percentage of pixels with passingγsignificantly differed under different minimum segment area,segment conversation and the spatial resolution in the measured dose distribution (all P<0.05).No significant correlation was observed between the passing rate and the minimum number of MU and the number of segment (P>0.05). Conclusions According to the actual situation of the equipment,the minimum segment area should be determined during IMRT planning. Direct machine parameter optimization should be performed. Appropriate resolution of the plane dose images can be chosen according to the minimum detector interval of dose matrix device.

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	Articles by authors
	Dai Liyan
	Wang Zhanyu
	Tan Junwen
	Gu Hengle
	Zhou Yun
	Long Yusong
	He Xiantao

Key words： Intensity-modulated radiation therapy &gamma analysis Dose verification

Received: 19 October 2017

Corresponding Authors: Wang Zhanyu,Email: wzyliuzhou@163.com

Cite this article:

Dai Liyan,Wang Zhanyu,Tan Junwen et al. Preliminary study of effect of multiple factors of intensity-modulated radiation therapy on dose verification[J]. Chinese Journal of Radiation Oncology, 2018, 27(10): 933-936.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2018.10.013 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2018/V27/I10/933

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