CT及3.0T MRI在食管癌IMRT中的价值

doi:10.3760/cma.j.issn.1004-4221.2017.11.007

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Abstract

Objective To investigate the significance of computed tomography (CT) and 3.0 T magnetic resonance imaging (MRI) in intensity-modulated radiotherapy (IMRT) for esophageal carcinoma. Methods Thirty-five patients newly diagnosed with esophageal carcinoma who received radical radiotherapy in our hospital from November 2013 to April 2015 were enrolled as subjects. Target volume was delineated on the CT images and MRI images (T2-weighted and diffusion-weighted fusion images). The MRI-and CT-based IMRT plans were designed using the same dose prescription and dose constraints for organs at risk (OAR). The target volume,prescribed dose,and doses for OAR were compared between the two plans. Resutls In the two plans,dose distribution and planning parameters met the clinical requirement. The length of lesion,gross tumor volume (GTV),and planning target volume (PTV) defined by 3.0 T MRI were significantly smaller than those defined by CT (P=0.00,0.03,0.03). There were no significant differences in the D2%,D98%,D50%,homogeneity index,or conformity index for primary GTV (PGTV) and PTV-PGTV between the two plans (all P>0.05). Compared with the CT-based plan,the 3.0 T MRI-based plan had a significantly smaller mean dose to the lungs and an insignificantly smaller actual dose to the lungs (P=0.00;P>0.05). There were no significant differences in maximum doses tolerated by the spinal cord or heart between the two plans. Conclutions In terms of target volume delineation and dosimetric parameters,both CT-and 3.0 T MRI-based plans meet the clinical requirement. The 3.0 T MRI-based plan may provide potential benefits for some OAR due to a smaller target volume compared with the CT-based plan.

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	Articles by authors
	Huang Yifan
	Qian Liting
	Zhou Jieping
	Gao Jin
	Tao Zhenchao
	Zhou Yan
	Yang Liping
	He Jian
	Yang Jing
	Wang Ru
	Zhang Yangyang

Key words： Tomography,X-ray computed Magnetic resonance imaging Oesophageal neoplasms/intensity-modulated radiotherapy

Received: 08 May 2017

Corresponding Authors: Qian Liting,Email:money2004@sina.com

Cite this article:

Huang Yifan,Qian Liting,Zhou Jieping et al. Significance of computed tomography and 3.0 T magnetic resonance imaging in intensity-modulated radiotherapy for esophageal carcinoma[J]. Chinese Journal of Radiation Oncology, 2017, 26(11): 1276-1279.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2017.11.007 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2017/V26/I11/1276

[1] Hunter KU,Eisbruch A.Advances in imaging:target delineation[J].Cancer J,2011,17(3):151-154.DOI:10.1097/PPO.0b013e31821 d7e35.
[2] Rusten E,Rekstad BL,Undseth C,et al. Target delineation of anal cancer based on MR or PET-an inter-observer,inter-modality study[J].Radiother Oncol,2016,119(1):S336-S337.DOI:10.1016/S0167-8140(16)31969-7.
[3] Yang C,Chen Y.SU-F-I-51:CT/MR image deformation:the clinical assessment QA in target delineation[J].Med Phys,2016,43(6):3398.DOI:10.1118/1.4955879/abstract.
[4] Akay S,Kocaoglu M,Emer O,et al. Diagnostic accuracy of whole-body diffusion-weighted magnetic resonance imaging with3.0 Tin detection of primary and metastatic neoplasms[J].J Med Imaging Radiat Oncol,2013,57(3):274-282.DOI:10.1111/1754-9485.12026.
[5] Sillah K,Williams LR,Laasch HU,et al. Computed tomography overestimation of esophageal tumor length:implications for radiotherapy planning[J].World J Gastrointest Oncol,2010,2(4):197-204.DOI:10.4251/wjgo.v2.i4.197.
[6] Moghanaki D,Turkbey B,Vapiwala N,et al. Advances in prostate cancer magnetic resonance imaging and positron emission tomography-computed tomography for staging and radiotherapy treatment planning[J].Semin Radiat Oncol,2016,27(1):21-23.DOI:10.1016/j.semradonc.2016.08.008.
[7] Balbo-Mussetto A,Cirillo S,Bruna R,et al. Whole-body MRI with diffusion-weighted imaging:a valuable alternative to contrast-enhanced CT for initial staging of aggressive lymphoma[J].Clin Radiol,2015,71(3):271-279.DOI:10.1016/j.crad.2015.11.018.
[8] Aoyagi T,Shuto K,Okazumi S,et al. Apparent diffusion coefficient values measured by diffusion-weighted imaging predict chemoradiotherapeutic effect for advanced esophageal cancer[J].Dig Surg,2011,28(4):252-257.DOI:10.1159/000328770.
[9] Hou DL,Shi GF,Gao XS,et al. Improved longitudinal length accuracy of gross tumor volume delineation with diffusion weighted magnetic resonance imaging for esophageal squamous cell carcinoma[J].Radiat Oncol,2013,8:169.DOI:10.1186/1748-717X-8-169.
[10] 田华,王澜,韩春,等.磁共振弥散加权成像在食管癌精确放疗中的应用价值[J].中华放射肿瘤学杂志,2012,21(3):223-226.DOI:10.3760/cma.j.issn.1004-4221.2012.03.009.
Tian H,Wang L,Han C,et al. Application of diffusion-weighted magnetic resonance imaging in precise radiotherapy for esophageal carcinoma[J].Chin J Radiat Oncol,2012,21(3):223-226.DOI:10.3760/cma.j.issn.1004-4221.2012.03.009.
[11] Huang W,Currey A,Chen XJ,et al. A comparison of lumpectomy cavity delineations between use of magnetic resonance imaging and computed tomography acquired with patient in prone position for radiation therapy planning of breast cancer[J].Int J Radiat Oncol Biol Phys,2016,94(4):832-840.DOI:10.1016/j.ijrobp.2015.12.014.
[12] 黄蓉,吴慧,卢晓旭,等.CT-MRI图像融合在脑胶质瘤术后精确放疗中的应用分析[J].中华放射肿瘤学杂志,2017,26(2):192-196.DOI:10.3760/cma.j.issn.1004-4221.2017.02.015.
Huang R,Wu H,Lu XX,et al. Observation of CT-MRI image fusion in postoperativeprecise radiotherapy for gliomas[J].Chin J Radiat Oncol,2017,26(2):192-196.DOI:10.3760/cma.j.issn.1004-4221.2017.02.015.
[13] Swanick CW,Castle KO,Vedam S,et al. Comparison of CT and MRI-Based clinical target volume contours at the time of brachytherapy for cervical cancer[J].Int J Radiat Oncol Biol Phys,2015,93(S3):E282.DOI:10.1016/j.ijrobp.2015.07.1259.
[14] 王澜,李晓宁,吕冬婕,等.肺低剂量区体积预测急性放射性肺炎价值探讨[J].中华放射肿瘤学杂志,2010,19(4):296-300.DOI:10.3760/cma.j.issn.1004-4221.2010.04.005.
Wang L,Li XN,Lv DJ,et al. Low dose volume of the lung in prediction of acute radiation pneumonitis[J].Chin J Radiat Oncol,2010,19(4):296-300.DOI:10.3760/cma.j.issn.1004-4221.2010.04.005.