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Understanding of radiation enteritis and its possible pathogenic mechanism
Zhang Ximei,Wang Peiguo,Yuan Zhiyong,Wang Ping
Department of Radiotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for cancer;Key Laboratory of Cancer Preventing and Therapy,Tianjin;Tianjin's Clinical Research Center for Cancer;Tianjin 300060,China
Abstract Radiation enteritis significantly affects the quality of life in the patients receiving radiotherapy due to pelvic tumor. As an intestinal inflammation related to radiotherapy, radiation enteritis is an inflammation of the mucous membrane in nature based on some basic research. Studies demonstrate that programmed necroptosis might play a role in the development of inflammatory bowel disease;therefore, as a subtype of inflammatory bowel disease, programmed necroptosis also might play a role in the development and progression of radiation enteritis. This paper aims to review the studies about the nature and pathogenic mechanism in order to contribute to the treatment of radiation enteritis and improve patients’ quality of life.
Zhang Ximei,Wang Peiguo,Yuan Zhiyong et al. Understanding of radiation enteritis and its possible pathogenic mechanism[J]. Chinese Journal of Radiation Oncology, 2017, 26(9): 1099-1102.
Zhang Ximei,Wang Peiguo,Yuan Zhiyong et al. Understanding of radiation enteritis and its possible pathogenic mechanism[J]. Chinese Journal of Radiation Oncology, 2017, 26(9): 1099-1102.
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2017, Vol. 26 
