IMRT不同剂量验证技术差异性分析

doi:10.3760/cma.j.issn.1004-4221.2017.06.011

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Abstract Objective To compare the dosimetric verification results of Varian Portal Dosimetry and Matrixx, and to assess the reliability of the clinical application of electronic portal imaging device (EPID) verification. Methods Varian TrueBeam linear accelerator, which was equipped with a 120-leaf multileaf collimator and an amorphous silicon EPID, as well as portal dose prediction software. IBA I′mRT Matrixx ion chamber array was used. EPID algorithm configuration, dose calibration, and testing before use were performed. The sliding-window protocol was used. There were 77 patients with tumors involving the head and neck (mainly nasopharyngeal carcinoma), mediastinum, abdomen, and pelvic cavity were selected. The verification plan of the portal dose was created with a source-detector distance of 100 cm, and the gantry angle was kept the same as the treatment plan. The verification plan was carried out in the TrueBeam machine, and the data were collected at the same time by EPID. Comparison between the measured and calculated dose images was performed, and the evaluation standard was gamma index (3%/3 mm). The paired t-test was used for difference analysis. Results For the 77 patients,the Gamma passing rates of both methods were above 97%. Except for head and neck carcinoma were a significant difference between the results of dosimetric results using EPID and Matrixx in intensity-modulated radiotherapy (P=0.018) other remaining all P> 0.05. Conclusions The dosimetric verification results of EPID are consistent with those of Matrixx. EPID can be used for dosimetric verification, and Matrixx ion chamber array can be used only in case of a low Gamma passing rate.

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	Articles by authors
	Guo yuexin
	Pei yuntong
	Ma yangguang
	Jia fei
	Wang haiyang

Key words： Dosimetric verification Portal dosimetry Matrixx

Received: 01 September 2016

Cite this article:

Guo yuexin,Pei yuntong,Ma yangguang et al. A comparative analysis of Matrixx and EPID for dosimetric verification of intensity-modulated radiotherapy[J]. Chinese Journal of Radiation Oncology, 2017, 26(6): 657-660.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2017.06.011 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2017/V26/I6/657

[1] Buonamici FB,Compagnucci A,Marrazzo L,et al. An intercomparison between film dosimetry and diode matrix for IMRT quality assurance[J].Med Phys,2007,34(4):1372-1379.DOI:10.1118/1.2713426.
[2] Schreibmann E,Dhabaan A,Elder E,et al. Patient-specific quality assurance method for VMAT treatment delivery[J].Med Phys,2009,36(10):4530-4535.DOI:10.1118/1.3213085.
[3] van Elmpt W,McDermott L,Nijsten S,et al. A literature review of electronic portal imaging for radiotherapy dosimetry[J].Radiother Oncol,2008,88(3):289-309.DOI:10.1016/j.radonc.2008.07.008.
[4] McDermott LN,Louwe RJW,Sonke JJ,et al. Dose-response and ghosting effects of an amorphous silicon electronic portal imaging device[J].Med Phys,2004,31(2):285-295.DOI:10.1118/1.1637969.
[5] Warkentin B,Steciw S,Rathee S,et al. Dosimetric IMRT verification with a flat-panel EPID[J].Med Phys,2003,30(12):3143-3155.DOI:10.1118/1.1625440.
[6] Varian medical systems. Reference guide.[Product no B500284R01C].Portal Imaging and Portal Dosimetry,2008.
[7] Low DA,Harms WB,Mutic S,et al. A technique for the quantitative evaluation of dose distributions[J].Med Phys,1998,25(5):656-661.DOI:10.1118/1.598248.
[8] Persoon LCGG,Podesta M,van Elmp WJC,et al. A fast three-dimensional gamma evaluation using a GPU utilizing texture memory for on-the-fly interpolations[J].Med Phys,2011,38(7):4032-4035.DOI:10.1118/1.3595114.
[9] Vieira SC,Dirkx ML,Heijmen BJM,et al. SIFT:a method to verify the IMRT fluence delivered during patient treatment using an electronic portal imaging device[J].Int J Radiat Oncol Biol Phys,2004,60(3):981-993.DOI:10.1016/j.ijrobp.2004.06.025.
[10] Van Esch A,Depuydt T,Huyskens P.The use of an aSi-based EPID for routine absolute dosimetric pre-treatment verification of dynamic IMRT fields[J].Radiother Oncol,2004,71(2):223-234.DOI:10.1016/j.radonc.2004.02.018.
[11] McCurdy BMC,Luchka K,Pistorius S.Dosimetric investigation and portal dose image prediction using an amorphous silicon electronic portal imaging device[J].Med Phys,2001,28(6):911-924.DOI:10.1118/1.1374244.
[12] Winkler P,Hefner A,Georg D.Dose-response characteristics of an amorphous silicon EPID[J].Med Phys,2005,32(10):3095-3105.DOI:10.1118/1.2040711.
[13] Greer PB,Popescu CC.Dosimetric properties of an amorphous silicon electronic portal imaging device for verification of dynamic intensity modulated radiation therapy[J].Med Phys,2003,30(7):1618-1627.DOI:10.1118/1.1582469.
[14] Cozzi L,Fogliata A,Nicolini G.Pre-treatment verification of intensity modulated photon beams with films and electronic portal imaging-two years of clinical experience[J].Z Med Phys,2004,14(4):239-250.DOI:10.1078/0939-3889-00226.
[15] El-Mohri Y,Antonuk LE,Yorkston J,et al. Relative dosimetry using active matrix flat-panel imager (AMFPI) technology[J].Med Phys,1999,26(8):1530-1541.DOI:10.1118/1.598649.
[16] Steciw S,Warkentin B,Rathee S,et al. Three-dimensional IMRT verification with a flat-panel EPID[J].Med Phys,2005,32(2):600-612.DOI:10.1118/1.1843471.
[17] Grzdziel A,Smolińska B,Rutkowski R,et al. EPID dosimetry-configuration and pre-treatment IMRT verification[J].Rep Pract Oncol Radiother,2007,12(6):307-312.DOI:10.1016/S1507-1367(10)60069-7.
[18] Sharma DS,Mhatre V,Heigrujam M,et al. Portal dosimetry for pretreatment verification of IMRT plan:a comparison with 2D ion chamber array[J].J Appl Clin Med Phys,2010,11(4):3268.DOI:10.1120/jacmp.v11i4.3268.
[19] Bakhtiari M,Kumaraswamy L,Bailey DW,et al. Using an EPID for patient-specific VMAT quality assurance[J].Med Phys,2011,38(3):1366-1373.DOI:10.1118/1.3552925.
[20] Bailey DW,Kumaraswamy L,Bakhtiari M,et al. EPID dosimetry for pretreatment quality assurance with two commercial systems[J].J Appl Clin Med Phys,2012,13(4):82-99.DOI:10.1120/jacmp.v13i4.3736.