[1] Jain S,Hirst DG,O'Sullivan JM.Gold nanoparticles as novel agents for cancer therapy[J].Br J Radiol,2012,85(1010):101-113.DOI:10.1259/bjr/59448833. [2] Khoshgard K,Hashemi B,Arbabi A,et al. Radiosensitization effect of folate-conjugated gold nanoparticles on HeLa cancer cells under orthovoltage superficial radiotherapy techniques[J].Phys Med Biol,2014,59(9):2249-2263.DOI:10.1088/0031-9155/59/9/2249. [3] Kao H W,Lin Y Y,Chen C C,et al. Biological characterization of cetuximab-conjugated gold nanoparticles in a tumor animal model[J].Nanotechnology,2014,25(29):295102.DOI:10.1088/0957-4484/25/29/295102. [4] Kao H W,Lin Y Y,Chen C C,et al. Evaluation of EGFR-targeted radioimmuno-gold-nanoparticles as a theranostic agent in a tumor animal model[J].Bioorg Med Chem Lett,2013,23(11):3180-3185.DOI:10.1016/j.bmcl.2013.04.002. [5] Roa W,Zhang X J,Guo L H,et al. Gold nanoparticle sensitize radiotherapy of prostate cancer cells by regulation of the cell cycle[J].Nanotechnology,2009,20(37):375101.DOI:10.1088/0957-4484/20/37/375101. [6] 杨华,郑勤,朱传东,等.纳米颗粒对人肝癌HepG2细胞放射增敏效应的实验研究[J].中华放射肿瘤学杂志,2012,21(6):571-574.DOI:10.3760/cma.j.issn.1004-4221.2012.06.026. Yang H,Zheng Q,Zhu CD,et al. Experimental study on the effect of nano particles on the radiation sensitivity of human hepatocellular carcinoma HepG2 cells[J].Chin J Radiat Oncol,2012,21(6):571-574.DOI:10.3760/cma.j.issn.1004-4221.2012.06.026. [7] Hitomi J,Katayama T,Eguchi Y,et al. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death[J].J Cell Biol,2004,165(3):347-356.DOI:10.1083/jcb.200310015. [8] Tsai Y Y,Huang Y H,Chao Y L,et al. Identification of the nanogold particle-induced endoplasmic reticulum stress by omic techniques and systems biology analysis[J].ACS Nano,2011,5(12):9354-9369.DOI:10.1021/nn2027775. [9] Yasui H,Takeuchi R,Nagane M,et al. Radiosensitization of tumor cells through endoplasmic reticulum stress induced by PEGylated nanogel containing gold nanoparticles[J].Cancer Lett,2014,347(1):151-158.DOI:10.1016/j.canlet.2014.02.005. [10] Chatterjee S,Hirota H,Belfi CA,et al. Hypersensitivity to DNA cross-linking agents associated with up-regulation of glucose-regulated stress protein GRP78[J].Cancer Res,1997,57(22):5112-5116. [11] NoёlC,Simard JC,Girard D.Gold nanoparticles induce apoptosis,endoplasmic reticulum stress events and cleavage of cytoskeletal proteins in human neutrophils[J].Toxicol Vitro,2016,31:12-22.DOI:10.1016/j.tiv.2015.11.003.
2017, Vol. 26 
