间歇式屏气CBCT图像采集优选模式研究

doi:10.3760/cma.j.issn.1004-4221.2017.01.013

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Abstract

Objective To develop a practical image acquisition strategy using intermittent breath-hold cone beam computed tomography (CBCT). Methods A breathing phantom was used to simulate the movement of tumor near the diaphragm during free breathing and breath hold and scanned by conventional breath-hold CBCT and type Ⅰ/Ⅱ intermittent breath-hold CBCT. In the conventional breath-hold CBCT, scan paused and free breathing occurred at the break of breath hold and free breathing was not included in the scan. In the intermittent breath-hold CBCT, one scan covered several breath holds separated by free breathing in a ratio of 3 vs1. Image quality and three-dimensional registration accuracy were quantitatively compared between conventional breath-hold CBCT and type Ⅰ/Ⅱ intermittent breath-hold CBCT. Comparison of image quality parameters between conventional breath-hold CBCT and intermittent breath-hold CBCT was made by paired t test. Results Motion artifacts arose in type I and Ⅱ intermittent breath-hold CBCT scans. There were no significant differences in the reconstructed pixel value or uniformity between intermittent breath-hold CBCT and conventional breath-hold CBCT (P>0.05, and P=0.02,0.53). Compared with conventional breath-hold CBCT images, the signal-to-noise ratios of type I and Ⅱ intermittent breath-hold CBCT images were reduced by 30% and 60%, respectively (P<0.05). The registration errorwas up to 0.4 cm in the anterior-posterior direction and less than 0.1 cm in other directions. ConclusionsThe phantom study shows that intermittent breath-hold CBCT does not significantly reduce image quality or registration accuracy compared with conventional breath-hold CBCT. The feasibility of intermittent breath-hold CBCT in clinical application needs to be further validated among a large number of patients.

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	Articles by authors
	Wang Juanqi
	Hu Weigang
	Peng Jiayuan
	Luo Ji

Key words： Breath-hold Tomography,X-ray computed,cone beam Respiratory motion

Received: 25 August 2015

Fund:

National Natural Science Foundation of China (11205033)

Corresponding Authors: Hu Weigang,Email:jackhuwg@gmail.com

Cite this article:

Wang Juanqi,Hu Weigang,Peng Jiayuan et al. Investigation of image guidance strategy for intermittent breath-hold cone beam CT[J]. Chinese Journal of Radiation Oncology, 2017, 26(1): 57-61.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2017.01.013 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2017/V26/I1/57

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