3D打印技术在CT引导宫颈癌术后阴道残端肿瘤近距离治疗中应用

doi:10.3760/cma.j.issn.1004-4221.2016.09.013

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Abstract Objective To investigate the application of 3D printing technology in the manufacture of individualized source applicator for intraluminal brachytherapy. Methods A retrospective analysis was performed for the clinical data of one patient with vaginal stump stenosis and regular solid tumor after cervical carcinoma surgery. The gauze soaked in the developer was used for vaginal packing, and then CT scan was performed to obtain the three-dimensional intraluminal geometric outline of the vagina. A software was used to extract the outline, and 3 lumens were reserved near the lesion. The 3D printer and medical silica gel were used to manufacture the source applicator. The source applicator was placed in the vagina, and CT scan was performed to adjust the position of the source applicator. The final CT image was transferred to the planning system for the delineation of target volume and organs at risk and calculate dose distribution. Results The individualized vaginal source applicator manufactured by 3D printing technology fitted well to the target volume, and the curvature of the catheters was greater than 1 cm, so that the radioactive source could pass successfully. The inserted catheters were cut, and the total operative length of the radioactive source was set to be 1 280 mm, which helped to realize the accurate connection between the individualized source applicator and the afterloader. At the same time when the prescribed dose was reached in the lesion, the bladder and rectal D_{2 cm³} was 320.4 cGy and 331.5 cGy, respectively, which did not exceed the dose limits. Conclusions The individualized source application manufactured by 3D printing technology is applicable to the treatment of patients with vaginal stump stenosis and regular solid tumor after cervical carcinoma surgery, and its clinical effect and adverse effects await further investigation.

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	Articles by authors
	Yu Lang
	Lian Xin
	Yan Junfang
	Luo Chunli
	He Lei
	Zhang Yue
	Wang Guanqun
	Li Hongming
	Yang Bo
	Hu Ke
	Qiu Jie
	Zhang Fuquan

Key words： Vaginal mold Three-dimensional printing technique Individual applicator

Received: 16 December 2015

Corresponding Authors: Qiu Jie,Email:qj_ww@139.com

Cite this article:

Yu Lang,Lian Xin,Yan Junfang et al. Application of 3D printing technology in brachytherapy for vaginal stump tumor after CT-guided cervical carcinoma surgery[J]. Chinese Journal of Radiation Oncology, 2016, 25(9): 965-967.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2016.09.013 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2016/V25/I9/965

[1] Small Jr W,Beriwal S,Demanes DJ,et al. American Brachytherapy Society consensus guidelines for adjuvant vaginal cuff brachytherapy after hysterectomy[J].Brachytherapy,2012,11(1):58-67.DOI:10.1016/j.brachy.2011.08.005.
[2] Beriwal S,Demanes DJ,Erickson B,et al. American Brachytherapy Society consensus guidelines for interstitial brachytherapy for vaginal cancer[J].Brachytherapy,2012,11(1):68-75.DOI:10.1016/j.brachy.2011.06.008.
[3] Nilsson S,Moutrie Z,Cheuk R,et al A unique approach to high-dose-rate vaginal mold brachytherapy of gynecologic malignancies[J].Brachytherapy,2015,14(2):267-272.DOI:10.1016/j.brachy.2014.10.004.
[4] Sethi R,Cunha JAN,Mellis K,et al.3D printed custom applicator for high-dose-rate intracavitary vaginal cuff brachytherapy[J].Brachytherapy,2014,13(S1):S93.DOI:10.1016/j.brachy.2014.02.371.
[5] 侯晓荣,于浪,单书灿,等.子宫内膜癌单通道和六通道柱状施源器三维近距离照射的剂量学比较[J].中华放射肿瘤学杂志,2015,24(1):60-64.DOI:10.3760/cma.j.issn.1004-4221.2015.01.017.
Hou XR,Yu L,Shan SC,et al. Dosimetric comparison between single-channel and six-channel vaginal cylinders with three-dimensional treatment planning in postoperative brachytherapy for endometrial carcinoma[J].China J Radiat Oncol,2015,24(1):60-64.DOI:10.3760/cma.j.issn.1004-4221.2015.01.017.
[6] Wiebe E,Easton H,Thomas G,et al. Customized vaginal vault brachytherapy with computed tomography imaging-derived applicator prototyping[J].Brachytherapy,2015,14(3):380-384.DOI:10.1016/j.brachy.2014.12.006.
[7] Garg A,Patil S,Siauw T,et al. An algorithm for computing customized 3D printed implants with curvature constrained channels for enhancing intracavitary brachytherapy radiation delivery[A]//Proceedings of 2013 IEEE International Conference on Automation Science and Engineering (CASE)[C].Madison,WI:IEEE,2013:466-473.DOI:10.1109/CoASE.2013.6654002.
[8] Pompeu-Robinson A,Kunz M,Falkson CB,et al. Immobilization and catheter guidance for breast brachytherapy[J].Int J Comput Assist Radiol Surg,2012,7(1):65-72.DOI:10.1007/s11548-011-0600-6.
[9] 佟岱,黄明伟,张建国,等.计算机辅助设计与快速成形技术制作上颌放射性粒子布源器的临床应用[J].北京大学学报:医学版,2010,42(1):63-66.DOI:10.3969/j.issn.1671-167X.2010.01.015.
Tong D,Huang MW,Zhang JG,et al. Clinical application of computer-aided design and rapid prototyping technique for radioactive seeds contained maxillary device[J].J Peking Univ:Health Sci,2010,42(1):63-66.DOI:10.3969/j.issn.1671-167X.2010.01.015.