Abstract Objective To study three contouring approaches of the bowel and evaluate the bowel dose volume with cervical cancer patient. Methods Twelve patients were selected,prescribed dose 45 Gy/25f. For each patient we contoured the bowel according to three different definitions:bowel loops,bowel bag and peritoneal space. Then we generated three rival plans each considering a different bowel definition and to evaluate dose differences of the HI,CI of PTV and Dmax,Dmean,V5-V45 of bowel loops with paired t-test. Results Comparison between BL and BB plan,Dmax,HI and CI of PTV,V5-V45 of bowel loops were not significantly different (P=0.171,0.076,0.192,P=0.315-0.855),Dmean of PTV and Dmax of bowel loops had difference (P=0.017,0.038).Comparison between BL and PS plan,Dmax, Dmean,HI and CI of PTV and Dmax of bowel loops had differences (P=0.033,0.044,0.046,0.041,0.013),V5-V45 of bowel loops were not significantly different (P=0.416-0.977).If the bowel loops V40≤15%,and bowel bag and peritoneal space V40≤20%. Conclusions All definitions provided a very similar dose volume of bowel loops. Taking into account HI and CI of PTV and max dose of bowel loops,BB seems better than PS.
Corresponding Authors:
Lu Xueguan,Email:luxueguan@163.com
Cite this article:
Sun Yanze,Zhou Gang,Qian Jianjun et al. The comparison of three bowel delineation strategies in the radiation therapy of cervical cancer[J]. Chinese Journal of Radiation Oncology, 2016, 25(1): 67-70.
Sun Yanze,Zhou Gang,Qian Jianjun et al. The comparison of three bowel delineation strategies in the radiation therapy of cervical cancer[J]. Chinese Journal of Radiation Oncology, 2016, 25(1): 67-70.
[1]Kavanagh BD,Pan CC,Dawson LA,et al. Radiation dose-volume effects in the stomach and small bowel[J].Int J Radiat Oncol Biol Phys,2010,76(3 Suppl):S101-S107.DOI:10.1016/j.ijrobp.2009.05.071. [2]Banerjee R,Chakraborty S,Nygren I,et al. Small bowel dose parameters predicting grade ≥3 acute toxicity in rectal cancer patients treated with neoadjuvant chemoradiation:an independent validation study comparing peritoneal space versus small bowel loop contouring techniques[J].Int J Radiat Oncol Biol Phys,2013,85(5):1225-1231.DOI:10.1016/j.ijrobp.2012.09.036. [3]郭玉燕,张纬建.直肠癌术前放疗小肠评价指标的研究进展[J].福建医药杂志,2013,35(3):154-156.DOI:10.3969/j.issn.1002-2600.2013.03.069. Guo YY,Zhang WJ.Research progress in evaluation indexes of small intestine of preoperative radiotherapy in rectal cancer[J].Fujian Med J,2013,35(3):154-156.DOI:10.3969/j.issn.1002-2600.2013.03.069. [4]Gay HA,Barthold HJ,O’Meara E,et al. Pelvic normal tissue contouring guidelines for radiation therapy:a Radiation Therapy Oncology Group consensus panel atlas[J].Int J Radiat Oncol Biol Phys,2012,83(3):e353-e362.DOI:10.1016/j.ijrobp.2012.01.023. [5]Hysing LB,Kvinnsland Y,Lord H,et al. Planning organ at risk volume margins for organ motion of the intestine[J].Radiother Oncol,2006,80(3):349-354.DOI:10.1016/j.radonc.2006.07.039. [6]Kvinnsland Y,Muren LP.The impact of organ motion on intestine doses and complication probabilities in radiotherapy of bladder cancer[J].Radiother Oncol,2005,76(1):43-47.DOI:10.1016/j.radonc.2005.06.007. [7]Dominello MM,Nalichowski A,Paximadis P,et al. Limitations of the bowel bag contouring technique in the definitive treatment of cervical cancer[J].Pract Radiat Oncol,2014,4(1):e15-e20.DOI:10.1016/j.prro.2013.04.003. [8]Sanguineti G,Little M,Endres EJ,et al. Comparison of three strategies to delineate the bowel for whole pelvis IMRT of prostate cancer[J].Radiother Oncol,2008,88(1):95-101.DOI:10.1016/j.radonc.2008.01.015. [9]Dolezel M,Odrazka K,Vanasek J,et al. MRI-based pre-planning in patients with cervical cancer treated with three-dimensional brachytherapy[J].Br J Radiol,2011,84(1005):850-856.DOI:10.1259/bjr/75446993. [10]Wiesendanger-Wittmer EM,Sijtsema NM,Muijs CT,et al. Systematic review of the role of a belly board device in radiotherapy delivery in patients with pelvic malignancies[J].Radiother Oncol,2012,102(3):325-334.DOI:10.1016/j.radonc.2012.02.004.
2016, Vol. 25 
