基于DVH目标函数的VMAT计划设计研究

doi:10.3760/cma.j.issn.1004-4221.2015.06.022

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Abstract Objective To study the novel Methods of VMAT planning based dose volume histogram (DVH) optimization, evaluated the dosimetry and planning efficiency in VMAT planning for Esophageal Carcinoma. Methods Twelve Esophageal carcinoma patients were enrolled in this study. The conventional VMAT planning as the reference, using multi-criterion optimization DVH (MCO-DVH) and overlapping volume histogram prediction DVH (OVH-DVH) two different Methods to get ideal objectives function for informing VMAT plans, Then evaluate the dosimetric, planning efficiency for all new VMAT plans. The difference between the paired t-test groups. Results The two VMAT plans based DVH Objective function can meet the clinical needs. Compared with the conventional VMAT plan, Conformity index (CI) and Homogeneity index (0.77 vs.0.72, P=0.017 and 0.10 vs.0.12, P=0.047) is better in DVH informed plans;lung V₅ and spinal cord V₅₀ are better in MCO-DVH informed plan (54.66 vs.60.23, P=0.013 and 0.98 vs.0.49, P=0.037).Furthermore, the DVH informed plans had higher planning efficiency (8.2 vs.19.5, P=0.023).Conclusions DVH Objective informed VMAT Planning can achieve clinical needs with much uniform dose to target, lower OAR dose and higher planning efficiency.

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	Articles by authors
	Jin Jianhua
	Chu Kaijue
	Shan Haijiao
	Liu Haitao
	Wu Jianting
	Zhao Yongliang
	Cao Gufei

Key words： Volume modulated arc therapy Multi criteria optimization Overlapping dose volume histogram

Corresponding Authors: Shan Haijiao,Shanghai Jiao Tong University,Shanghai 201261,China

Cite this article:

Jin Jianhua,Chu Kaijue,Shan Haijiao et al. DVH Obejective informed Planning in volume modulated arc therapy[J]. Chinese Journal of Radiation Oncology, 2015, 24(6): 695-698.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2015.06.022 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2015/V24/I6/695

[1] Palma D,Vollans E,James K,et al. Volumetric modulated arc therapy for delivery of prostate radiotherapy:comparison with intensity-modulated radiotherapy and three-dimensional conformal radiotherapy[J].Int J Radiat Oncol Biol Phys,2008,72(4):996-1001.DOI:10.1016/j.ijrobp.2008.02.047.
[2] Oliver M,Ansbacher W,Beckham WA.Comparing planning time,delivery time and plan quality for IMRT,RapidArc and Tomotherapy[J].J Appl Clin Med Phys,2009,10(4):3068.DOI:10.1120/jacmp.v10i4.3068.
[3] Hodapp N.The ICRU Report 83:prescribing,recording and reporting photon-beam intensity-modulated radiation therapy (IMRT)[J].Strahlenther Onkol,2012,188(1):97-99.DOI:10.1007/s00066-011-0015-x.
[4] Craft DL,Hong TS,Shih HA,et al. Improved planning time and plan quality through multicriteria optimization for intensity-modulated radiotherapy[J].Int J Radiat Oncol Biol Phys,2012,82(1):e83-e90.DOI:10.1016/j.ijrobp.2010.12.007.
[5] Wu BB,Ricchetti F,Sanguineti G,et al. Patient geometry-driven information retrieval for IMRT treatment plan quality control[J].Med Phys,2009,36(12):5497-5505.DOI:10.1118/1.3253464.
[6] Feuvret L,No G,Mazeron JJ,et al. Conformity index:a review[J].Int J Radiat Oncol Biol Phys,2006,64(2):333-342.DOI:10.1016/j.ijrobp.2005.09.028.
[7] Wu BB,Pang DL,Simari P,et al. Using overlap volume histogram and IMRT plan data to guide and automate VMAT planning:A head and neck case study[J].Med Phys,2013,40(2):021714.DOI:10.1118/1.4788671.
[8] Wu BB,Ricchetti F,Sanguineti G,et al. Data-driven approach to generating achievable dose–volume Histogram objectives in intensity-modulated Radiotherapy planning[J].Int J Radiat Oncol Biol Phys,2011,79(4):1241-1247.DOI:10.1016/j.ijrobp.2010.05.026.
[9] Yang YD,Ford EC,Wu BB,et al. An overlap-volume-histogram based method for rectal dose prediction and automated treatment planning in the external beam prostate radiotherapy following hydrogel injection[J].Med Phys,2013,40(1):011709.DOI:10.1118/1.4769424.
[10] Bokrantz R.Multicriteria optimization for volumetric-modulated arc therapy by decomposition into a fluence-based relaxation and a segment weight-based restriction[J].Med Phys,2012,39(11):6712-6725.DOI:10.1118/1.4754652.
[11] Chen HX,Craft DL,Gierga DP.Multicriteria optimization informed VMAT planning[J].Med Dosim,2014,39(1):64-73.DOI:10.1016/j.meddos.2013.10.001.
[12] Alvarez-Moret J,Pohl F,Koelbl O,et al. Evaluation of volumetric modulated arc therapy (VMAT) with Oncentra MasterPlan for the treatment of head and neck cancer[J].Radiat Oncol,2010,5(1):110.DOI:10.1186/1748-717X-5-110.
[13] Li N,Zarepisheh M,Uribe-Sanchez A,et al. Automatic treatment plan re-optimization for adaptive radiotherapy guided with the initial plan DVHs[J].Phys Med Biol,2013,58(24):8725-8738.DOI:10.1088/0031-9155/58/24/8725.