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The characteristics and prognosis of meteastases to the breast from nasal cavity tumors
Qu Yuan, Yi Junlin, Huang Xiaodong, Wang Kai, Gao Li
Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021,China Corresponding author;Gao Li, Email:gaowh@cicams.ac.cn
Abstract Objective To detect the clinical features and prognostic factors of nasal cavity malignancy with breast metastasis. Methods 846 Patients with nasal cavity malignancy from January 1999 to December 2011 were enrolled, the clinical and pathological features, clinical diagnostic methods and prognostic factors for breast metastasis patients were analyzed. Results Six female cases (median age 25) were diagnosed with breast metastasis, including 3 rhabdomyosarcoma and 3 olfactory neuroblastoma;consisting 0.7% of the total 846 cases of primary nasal malignancy group. The metastasis were more likely to be multiple breast lesions with/without metastasis in other site. For the primary tumor, five patients received 66-72 Gy/30-33f of radical radiotherapy, one patient with rest rhabdomyosarcoma received 58 Gy of palliative radiation since breast metastasis was found after 14 Gy of radiation and breast mass resection were performed right after. For the breast metastasis, five of 6 patients received breast surgery, one patients with olfactory neuroblastoma received 6 cycles cyclophosphamide+adriamycin+vincristine chemotherapy. Median survival was 12.7 months. Conclusions For nasal cavity malignancy, breast metastasis more likely occur in younger female patients. Ultrasound may provide useful information in evaluating breast metastasis. Cases combined with metastasis except breast have unfavorable prognosis.
Qu Yuan,Yi Junlin,Huang Xiaodong et al. The characteristics and prognosis of meteastases to the breast from nasal cavity tumors[J]. Chinese Journal of Radiation Oncology, 2014, 23(5): 411-414.
Qu Yuan,Yi Junlin,Huang Xiaodong et al. The characteristics and prognosis of meteastases to the breast from nasal cavity tumors[J]. Chinese Journal of Radiation Oncology, 2014, 23(5): 411-414.
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