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Chinese Journal of Radiation Oncology  2023, Vol. 32 Issue (5): 481-487    DOI: 10.3760/cma.j.cn113030-20220414-00142
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Application of 4DCT-based lung functional imaging in radiotherapy for lung cancer
Zhong Wenjing, Li Ying, Cui Haixia
Department of Oncology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016,China
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Abstract  Radiation pneumonia is a side effect that cannot be ignored in the current radiation therapy for lung cancer. At present, there are studies and reports of the introduction of functional imaging technology into lung cancer radiotherapy plans, in which 4DCT has better application prospects in radiotherapy for lung cancer because of its advantages of simple operation, high spatial resolution and no additional cost, etc. Compared with single-photon emission computed tomography (SPECT)-CT, positron emission tomography (PET)-CT, MRI has a better application prospect in radiotherapy of lung cancer. The use of 4DCT to obtain the patient's lung function status can predict radiation pulmonary toxicity and assist clinicians to deliver prompt interventions. Moreover, it can help carry out radiotherapy for functional lung avoidance, mitigate the damage of normal lung tissues, and alleviate chest toxicity, which may have wider application value in the future. In this article, research progress on functional lung imaging algorithms based on 4DCT and the application of radiation therapy for lung cancer was reviewed.
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Articles by authors
Zhong Wenjing
Li Ying
Cui Haixia
Key wordsLung neoplasms / radiotherapy      Radiation pneumonitis      Four-dimensional computed tomography      Functional lung      Ventilation image     
Received: 14 April 2022     
Corresponding Authors: Cui Haixia, Email: 204404@cqmu.edu.cn   
Cite this article:   
Zhong Wenjing,Li Ying,Cui Haixia. Application of 4DCT-based lung functional imaging in radiotherapy for lung cancer[J]. Chinese Journal of Radiation Oncology, 2023, 32(5): 481-487.
Zhong Wenjing,Li Ying,Cui Haixia. Application of 4DCT-based lung functional imaging in radiotherapy for lung cancer[J]. Chinese Journal of Radiation Oncology, 2023, 32(5): 481-487.
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