基于Halcyon 2.0和Truebeam的多部位VMAT计划剂量学质量与复杂度综合对比研究

doi:10.3760/cma.j.cn113030-20211108-00456

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Abstract Objective To analyze the differences in dosimetric quality and plan complexity of volumetric modulated arc therapy (VMAT) plans based on Halcyon 2.0 and Truebeam for different treatment sites of the patients. Methods Halcyon 2.0 VMAT plans in head & neck, chest, abdomen, and pelvis treatment sites of 49 cases were retrospectively selected and the VMAT plans were re‐designed based on Truebeam with the same optimization parameters. The differences in dosimetric metrics and plan complexity between the two types of plans were compared and analyzed. P<0.05 was considered as statistically significant. Results In terms of PTV, Halcyon 2.0 plans showed better homogeneity index (HI), conformal index (CI) in the head & neck and chest. Besides, Halcyon 2.0 plans yielded better D_98% and CI in the abdomen and better D_2% in the pelvis. For organs at risk (OAR), the D_20% and D_mean of bilateral lungs, and D_meanof heart for Halcyon 2.0 plans in the chest were lower than those for Truebeam plans (all P<0.05). For the complexity metrics, the median average aperture area variability (AAV) of Halcyon 2.0 plans in the head & neck, abdomen and pelvis were 0.414, 0.425 and 0.432, which were better than 0.385, 0.368 and 0.361 of Truebeam plans in the corresponding sites, respectively. In the abdomen and pelvis, Halcyon 2.0 plans showed better median modulation complexity score (MCS) than Truebeam plans (0.320 vs. 0.268, 0.303 vs. 0.282; both P<0.05). The median small aperture score (SAS) for all plans of Halcyon 2.0 were better than that of Truebeam plans (all P<0.05), and the median plan average beam area (PA) of all plans of Halcyon 2.0 were larger than that of Truebeam plans (all P<0.05). Conclusions Compared with conventional fractionated VMAT plans based on Halcyon 2.0 and Truebeam, Halcyon 2.0 plans have similar or even better dosimetric quality. However, Halcyon 2.0 plans have lower plan complexity, which makes it an advantage in clinical application.

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	Zhu Qizhen
	Yang Bo
	Wang Zhiqun
	Liang Yongguang
	Zhang Wenjun
	Gao Yuan
	Qiu Jie

Key words： Halcyon 2.0 linac Plan complexity Volumetric modulated arc therapy Dual‐layer multileaf collimator

Received: 08 November 2021

Fund:The China National Key R&D Program during the 13th Five‐year Plan Period (2016YFC0105206, 2016YFC0105207)

Corresponding Authors: Qiu Jie, Email: qiujie@pumch.cn

Cite this article:

Zhu Qizhen,Yang Bo,Wang Zhiqun et al. Comprehensive comparison between Halcyon 2.0 and Truebeam VMAT plans for different treatment sites: dosimetric quality and plan complexity[J]. Chinese Journal of Radiation Oncology, 2023, 32(3): 241-247.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.cn113030-20211108-00456 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2023/V32/I3/241

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