3D打印多通道施源器在宫颈癌术后患者近距离治疗中研究

doi:10.3760/cma.j.cn113030-20210712-00257

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Abstract Objective To compare the dosimetric difference between 3D-printed multi-channel applicator and conventional vaginal single-channel applicator for brachytherapy, aiming to provide guidance for patients receiving brachytherapy after cervical cancer surgery. Methods From January 2019 to November 2020, 25 cervical cancer patients complicated with VAIN Ⅲ receiving ¹⁹²Ir high-dose-rate brachytherapy after cervical cancer surgery were selected. Each patient was located by CT scanning with 3D-printed multi-channel applicator and conventional vaginal single-channel applicator, and corresponding plan and evaluation were carried out. The dose volume histogram (DVH) was obtained by inverse dose optimization algorithm. The dosimetric differences of high-risk clinical target volume (HRCTV), bladder and rectum during brachytherapy were compared with those of source applicators. The optimal treatment plan was selected. Results D90%, D100%, V100% and V150% of the plans designed by 3D-printed individual multi-channel applicator had no significant differences compared with those designed by conventional single-channel applicator (all P>0.05). The bladder and rectal D2cm³designed by 3D-printed multi-channel applicator were significantly lower than those using conventional single-channel applicator, and the differences were statistically significant (both P<0.05). Conclusion The multi-channel individual applicator target made by 3D-printing technology has good conformal property, properly protects the bladder and rectum and possesses treatment advantages over conventional single-channel applicator.

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	Articles by authors
	Tang Chengqiong
	Liu Jiangping
	Gulina Kuerban
	Liu Hao
	Cao Yaofeng
	Zhang Xiaofang
	Zhong Wei

Key words： 3D printing Multi-channel applicator Brachytherapy Inverse dose optimization

Received: 12 July 2021

Fund:Science and Technology Program Fund of Xinjiang Uygur Autonomous Region(2019D01C254)

Corresponding Authors: Zhong Wei, Email:68056068@qq.com

Cite this article:

Tang Chengqiong,Liu Jiangping,Gulina Kuerban et al. Study of 3D-printed multi-channel applicator in patients treated with brachytherapy after cervical cancer surgery[J]. Chinese Journal of Radiation Oncology, 2022, 31(5): 445-449.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.cn113030-20210712-00257 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2022/V31/I5/445

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