局限期小细胞肺癌预防性脑照射后脑转移相关危险因素分析

doi:10.3760/cma.j.cn113030-20210129-00049

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Abstract Small cell lung cancer (SCLC) has the biological characteristics of high recurrence and metastasis. The brain is the common site of SCLC extrapulmonary metastasis. Prophylactic cranial irradiation (PCI) can effectively reduce the incidence of brain metastasis and prolong the overall survival of patients with limited SCLC. Nevertheless, nearly one third of patients develop brain metastases after PCI. This article reviews the risk factors of brain metastasis after PCI, aiming to determine which subgroup of patients with limited SCLC can benefit from PCI and provide reference for the clinical application of PCI.

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	Li Mingxu
	Hu Songliu

Key words： Neoplasm, small cell lung Prophylactic cranial irradiation Brain metastasis Risk factor

Received: 29 January 2021

Fund:National Cancer Centre Climbing Fund (NCC201808B015);China Medical Hand in Hand Engineering Committee-Beijing Medical Award Foundation (YXJL-2020-0961-0159)

Corresponding Authors: Hu Songliu,Email:husongliu@126.com

Cite this article:

Li Mingxu,Hu Songliu. Analysis of risk factors associated with brain metastasis of limited small cell lung cancer after prophylactic cranial irradiation[J]. Chinese Journal of Radiation Oncology, 2022, 31(4): 395-399.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.cn113030-20210129-00049 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2022/V31/I4/395

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