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Exploration of combined application of three Varian OBI image-guided systems in image-guided radiotherapy for nasopharyngeal cancer
Zhang Bingxin, Shi Xiangli, Liang Guangli, Wang Wei
Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China
AbstractObjective To compare the comprehensive performance of three Varian on-board image (OBI) image systems (KV-CBCT, KV-planar and MV-EPID) and to explore the value of the combinedapplication of these three systems in daily image-guided radiotherapy for nasopharyngeal cancer. Methods KV-CBCT, KV-planar and MV-EPID scanning and registration were carried out in the left and right/abdominal and back/head and foot direction on human head and neck phantom. The set-up error, registration time, additional radiation dose and image quality of the three systems were compared by F-test. Results KV-CBCT,kV-planar and MV-EPID were scanned for 55 times, respectively, and the set-up errors in the left and right/abdominal and back/head and foot direction of the three image-guided systems were (0.00±5.43)/(-0.02±5.49)/(0.02±5.58)mm,(0.04±5.49)/(0.02±5.56)/(0.02±5.54)mm,(0.02±5.22)/(0.11±5.34)/(-0.04±5.33)mm,respectively (P=0.999,1.000, 0.989). The average time consuming was (200±45) s,(120±36) s and (115±42) s;the additional radiation dose from low to high was kV-planar, KV-CBCT and MV-EPID;the image quality from low to high was MV-EPID, kV-planar and KV-CBCT. Conclusions Three image-guided systems can meet the requirements of image-guided radiotherapy for nasopharyngeal cancer. Based on the overall performance of the three systems, 1 CBCT+4kV planar per week is recommended and EPID should be used as a backup system in daily image-guided radiotherapy for nasopharyngeal cancer. This scheme makes full use of the high image quality of CBCT and the low radiation of kV planar to realize the regular detection of nasopharyngeal cancer volume change and the implementation of high-precision radiotherapy.
Corresponding Authors:
Wang Wei, Email:weiwang_2@126.com
Cite this article:
Zhang Bingxin,Shi Xiangli,Liang Guangli et al. Exploration of combined application of three Varian OBI image-guided systems in image-guided radiotherapy for nasopharyngeal cancer[J]. Chinese Journal of Radiation Oncology, 2022, 31(4): 365-369.
Zhang Bingxin,Shi Xiangli,Liang Guangli et al. Exploration of combined application of three Varian OBI image-guided systems in image-guided radiotherapy for nasopharyngeal cancer[J]. Chinese Journal of Radiation Oncology, 2022, 31(4): 365-369.
[1] Zeidan OA, Langen KM, Meeks SL, et al. Evaluation of image-guidance protocols in the treatment of head and neck cancers[J]. Int J Radiat Oncol Biol Phys, 2007, 67(3):670-677. DOI:10.1016/j.ijrobp.2006.09.040. [2] Kupelian PA, Lee C, Langen KM, et al. Evaluation of image-guidance strategies in the treatment of localized prostate cancer[J]. Int J Radiat Oncol Biol Phys, 2008, 70(4):1151-1157. DOI:10.1016/j.ijrobp.2007.07.2371. [3] Duma MN, Kampfer S, Schuster T, et al. Do we need daily image-guided radiotherapy by megavoltage computed tomography in head and neck helical tomotherapy? The actual delivered dose to the spinal cord[J]. Int J Radiat Oncol Biol Phys, 2012, 84(1):283-288. DOI:10.1016/j.ijrobp.2011.10.073. [4] 肖青,钟仁明. 光学表面成像(OSI)在放疗中的应用与展望[J]. 中华放射肿瘤学杂志,2018, 27(2):214-217. DOI:10.3760/cma.j.issn.1004-4221.2018.02.020. Xiao Q, Zhong RM. Application and prospect of optical surface imaging (osi) in radiotherapy[J]. Chin J Radiat Oncol, 2018, 27(2):214-217. DOI:10.3760/cma.j.issn.1004-4221.2018.02.020. [5] Corradini S, Alongi F, Andratschke N, et al. MR-guidance in clinical reality:current treatment challenges and future perspectives[J]. Radiat Oncol, 2019, 14(1):92-98. DOI:10.1186/s13014-019-1308-y. [6] 孙鸿飞,倪昕晔,杨建华. 肿瘤超声引导下的放疗研究现状[J]. 中华放射肿瘤学杂志,2020, 29(4):317-320. DOI:10.3760/cma.j.cn113030-20181125-00014. Sun HF, Ni XY, Yang JH. Research status of ultrasound-guided radiotherapy for tumors[J]. Chin J Radiat Oncol, 2020, 29(4):317-320. DOI:10.3760/cma.j.cn113030-20181125-00014. [7] 刘利彬,吴君心,瞿宜艳,等. 千伏级锥形束CT与兆伏级电子摄野影像系统在鼻咽癌影像引导放疗的对比研究[J]. 中国医学物理学杂志,2012, 29(6):3721-3723,3741. DOI:10.3969/j.issn.1005-202X.2012.06.003. Liu LB, Wu JX, Qu YY, et al. Reserch and compare the application of the electronic portal imaging device and conebeamct in IGRT for the nasopharyngeal carcinoma patients[J]. Chin J Med Phys, 2012,29(6):3721-3723,3741. DOI:10.3969/j.issn.1005-202X.2012.06.003. [8] 陆维,许婷婷,许青,等. 应用CBCT、EPID研究鼻咽癌2种体位固定方式摆位误差的比较分析[J]. 中国癌症杂志,2014,24(7):535-539. DOI:10.3969/j.issn.1007-3969.2014.07.011. Lu W, Xu TT, Xu Q, et al. Comparison of set-up errors detected by EPID and CBCT using two different immobilization;techniques for patients with nasopharygeal carcinoma[J]. Chin Oncol, 2014, 24(7):535-539. DOI:10.3969/j.issn.1007-3969.2014.07.011. [9] 胡健,徐利明,姚颐,等. KV-KV、KV-MV和CBCT在头颈部调强放疗位置验证中的对比研究[J]. 中国医学物理学杂志,2010, 27(4):1988-1992. DOI:10.3969/j.issn.1005-202X.2010.04.010. Hu J, Xu LM, Yao Y, et al. The Comparation of 2D kilovoltage with kilovoltage-megavoltage radiographs and cone-beam computed tomography in position verification of head and neck intensity modulate radiotherapy[J]. Chin J Med Phys, 2010, 27(4):1988-1992. DOI:10.3969/j.issn.1005-202X.2010.04.010. [10] 李明辉,张寅,戴建荣,等. 千伏级X线透视成像与锥形束CT确定头颈部摆位误差的比较[J]. 中华放射肿瘤学杂志,2012, 21(4):374-376. DOI:10.3760/cma.j.issn.1004-4221.2012.04.023. Li MH, Zhang Y, Dai JR, et al. Comparing the performance of two methods to determine set-up errors for patients with head-and-neck cancer[J]. Chin J Radiat Oncol, 2012, 21(4):374-376. DOI:10.3760/cma.j.issn.1004-4221.2012.04.023. [11] 黄敏霞,沙朝丰,史安娜. 千伏级CBCT与X线透视成像校正鼻咽癌患者摆位误差相关性及一致性研究[J]. 浙江医学,2018, 40(18):2031-2033. DOI:10.12056/j.issn.1006-2785.2018.40.18.2018-933. Huang MX, Sha CF, Shi AN. Correlation and consistency between conebeam CT and orthogonal kV radiography in image-guided radiation therapy for nasopharyngeal carcinoma patients[J]. Zhejiang Med J, 2018, 40(18):2031-2033. DOI:10.12056/j.issn.1006-2785.2018.40.18.2018-933. [12] 康德华,邓小武,黄劭敏. 电子射野影像系统(EPIDs)图像质量控制方法的探索[J]. 中国医学物理学杂志,2009, 26(1):955-957. Kang DH, Deng XW, Huang SM. The quality control test for digital image of electronic portal imaging devices (EPIDs)[J]. Chin J Med Phys, 2009, 26(1):955-957. [13] 庄永东,王彬,朱金汉,等. 医用直线加速器机载影像系统QC图像定量评估方法研究[J]. 中华放射肿瘤学杂志,2017, 26(4):442-447. DOI:10.3760/cma.j.issn.1004-4221.2017.04.016. Zhuang YD, Wang B, Zhu JH, et al. A quantitative evaluation of quality control image for on-board imaging system of medical linear accelerator[J]. Chin J Radiat Oncol, 2017, 26(4):442-447. DOI:10.3760/cma.j.issn.1004-4221.2017.04.016. [14] Song WY, Kamath S, Ozawa S, et al. A dose comparison study between XVI and OBI CBCT systems[J]. Med Phys, 2008, 35(2):480-486. DOI:10.1118/1.2825619. [15] 张玉海,夏火生,高杨. 不同图像引导方式在头颈部肿瘤中成像剂量测量[J]. 中国医疗器械杂志,2010,34(6):455-457. DOI:10.3969/j.isnn.1671-7104.2010.06.020. Zhang YH, Xia HS, Gao Y. Measurement of the imaging dose for head and neck cancer by different image-guided methods[J]. Chin J Med Dev, 2010, 34(6):455-457. DOI:10.3969/j.isnn.1671-7104.2010.06.020. [16] 张立杰. 鼻咽癌精确放疗的研究进展[J]. 实用肿瘤学杂志,2013, 27(1):77-80. DOI:10.3969/j.issn.1002-3070.2013.01.017. Zhang LJ. The progress of precision radiotherapy in nasopharyngeal carcinoma[J]. J Pract Oncol, 2013, 27(1):77-80. DOI:10.3969/j.issn.1002-3070.2013.01.017. [17] 岳丹,杨永净,赵玲,等.kV-CBCT图像引导鼻咽癌调强放疗的精确性研究[J]. 中华放射医学与防护杂志,2016, 36(3):211-215. DOI:10.3760/cma.j.issn.0254-5098.2016.03.010. Yue D, Yang YJ, Zhao L, et al. Sclinical feasibility and accuracy of image guidance with kilovoltage cone-beam computed tomography in nasopharyngeal carcinoma intensity-modulated radiotherapy[J]. Chin J Radiol Med Protect, 2016 36(3):211-215. DOI:10.3760/cma.j.issn.0254-5098.2016.03.010. [18] Rampado O, Giglioli FR, Rossetti V, et al. Evaluation of various approaches for assessing dose indicators and patient organ doses resulting from radiotherapy cone-beam CT[J]. Med Phys, 2016, 43(5):2515-2526. DOI:10.1118/1.4947129. [19] Son K, Kim JS, Lee H, et al. Imaging dose of human organs from kv-cbct in image-guided radiation therapy[J]. RadiatProt Dosimetry, 2017, 175(2):194-200. DOI:10.1093/rpd/ncw285.