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Recent research progress on surgery combined with radiation therapy for primary liver cancer
Yang Yongqiang1, Chen Wei2, Tian Ye1
1Department of Radiotherapy and Oncology, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China; 2Department of Hepatobiliary Surgery, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China
Abstract Surgical resection is the main radical treatment of early and mid-stage primary liver cancer (PLC), but the high postoperative recurrence rate is the main factor affecting the curative effect. With recent advancement in techniques, the efficacy and safety of radiation therapy for PLC have been widely proven. In this review, we will investigate the combination of surgery and radiation therapy, covering the topics of preoperative or postoperative radiotherapy for PLC with portal vein tumor thrombus, postoperative adjuvant radiotherapy in PLC with narrow surgical margin or microvascular invasion, stereotactic body radiation therapy as a bridge to liver transplantation, radiotherapy in conversion to resectability for intrahepatic inoperable PLC. Despite radiation therapy is one of the effective therapeutic options for PLC, there is still a compelling need for prospective, randomized, controlled phase Ⅲ trials to acquire high-levelclinical evidence for confirming the role of radiation therapy in the treatment of PLC.
Fund:Jiangsu Medical Innovation Team (CXDT-37);Suzhou Introduced Project of Clinical Medical Expert Team (SZYJTD201803)
Corresponding Authors:
Chen Wei, Email:chenwei1971@vip.163.com;Tian Ye, Email:dryetian@126.com
Cite this article:
Yang Yongqiang,Chen Wei,Tian Ye. Recent research progress on surgery combined with radiation therapy for primary liver cancer[J]. Chinese Journal of Radiation Oncology, 2021, 30(7): 744-747.
Yang Yongqiang,Chen Wei,Tian Ye. Recent research progress on surgery combined with radiation therapy for primary liver cancer[J]. Chinese Journal of Radiation Oncology, 2021, 30(7): 744-747.
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