微生物群在放疗诱导损伤中的作用研究进展

doi:10.3760/cma.j.cn113030-20190829-00349

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Abstract Human microbiota is composed of bacteria, viruses, fungi and other microorganisms, which are distributed in the oral cavity, nasal cavity, intestine, vagina and skin, etc. Human microbiota plays a pivotal role in the metabolism, immunity, hormones and homeostasis of the host. It can protect the host and maintain the homeostasis, and provoke the incidence of inflammation and tumors. Microbiota has been found to modulate the efficacy and toxicity of chemotherapy and immunotherapy for certain types of tumors. Nevertheless, large-scale studies in the context of radiation therapy have not been performed. In this article, the relationship between the microbiota and the radiotherapy response and toxicity changes of cancer patients was summarized, aiming to develop the optimal treatment plan for patients, and provide evidence for the prevention and treatment of radiotherapy-induced injury.

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	Articles by authors
	Liu Jingli
	Li Lan
	Zhou Pengcheng
	Yang Juan
	Li Xiangrong
	Qu Guangqiao

Key words： Microbiota Radiotherapy-induced injury Neoplasm/radiotherapy

Received: 29 August 2019

Corresponding Authors: Li Lan, Email:1219067429@qq.com

Cite this article:

Liu Jingli,Li Lan,Zhou Pengcheng et al. Research progress on the role of microbiota in radiotherapy-induced injury[J]. Chinese Journal of Radiation Oncology, 2021, 30(5): 531-534.

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http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.cn113030-20190829-00349 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2021/V30/I5/531

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