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Research progress on dosimetry-related long-term complications of pediatric cancer radiotherapy
Qiu Wenlong1, Shi Pengyue2, Wang Jingfu3, Zhu Jian1, Yu Jinming4
1Department of Radiation Oncology Physics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan 250117, China; 2Department of Abdominal Radiation Oncology Ⅰ, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan 250117, China; 3Department of Pediatric Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan 250117, China; 4Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Ji'nan 250117, China
Abstract Children with pediatric tumors have better prognosis and longer survival than adults, suggesting that attention should be paid to the long-term complications induced by radiotherapy. In this article, the data from more than 40 clinical studies of pediatric tumor radiotherapy published in the recent decade were retrospectively analyzed. Long-term complications of nervous system, cardio-cerebrovascular system, respiratory system, endocrine system, urinary system, reproductive system, skeletal development, long-term secondary tumors were considered and the corresponding radiation dose-volume parameters were summarized, aiming to guide radiation oncology physicians and physicists to optimize radiotherapy plans for children with pediatric tumors.
Fund:Shandong Provincial Natural Science Foundation (ZR2020LZL001);Foundation of Taishan Scholars of Shandong Province (tsqn201909140);Academic Promotion Program of Shandong First Medical University (2020RC003);National Key Research and Development Program (2018YFC1313201)
Qiu Wenlong,Shi Pengyue,Wang Jingfu et al. Research progress on dosimetry-related long-term complications of pediatric cancer radiotherapy[J]. Chinese Journal of Radiation Oncology, 2021, 30(4): 413-418.
Qiu Wenlong,Shi Pengyue,Wang Jingfu et al. Research progress on dosimetry-related long-term complications of pediatric cancer radiotherapy[J]. Chinese Journal of Radiation Oncology, 2021, 30(4): 413-418.
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