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Analysis of psychological distress in elderly patients with head and neck cancer receiving radiotherapy
Bao Ruizhi, Yi Junlin, Liu Qingfeng, Chen Xuesong, Wu Runye, Huang Xiaodong, Wang Kai, Qu Yuan, Zhang Shiping, Luo Jingwei, Xiao Jianping, Zhang Ye
Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/ Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
AbstractObjective To evaluate the psychological pain of patients with head and neck cancer aged ≥60 years old before and after intensity-modulated radiotherapy (IMRT). Methods Distress Thermometer (DT)(Chinese version) was used to investigate the degree and problems of psychological pain before and after IMRT for 85 elderly patients with head and neck cancer. The results before and after IMRT were compared by paired t-test. Relevant factors were identified by Logistic regression analysis. Results The median age in the cohort was 66 years old (60-85 years old). The incidence rates of psychological pain were 73% and 87% before and after IMRT (P<0.001). The corresponding incidence rates of severe distress were 6% and 34%(P<0.001). The main distress problems before IMRT were memory loss/attention deficit, worry, oral pain, economic problems, stress, sleep problems, and dry nose. The significantly-increased distress problems after IMRT were oral pain, constipation, eating, nausea, and dry nose. Logistic regression analysis showed gender (OR=5.520, 95%CI 1.437-21.212, P=0.013), pre-treatment PG-SGA score (OR=1.220, 95%CI 1.048-1.421, P=0.010) and medical insurance (OR=0.230, 95%CI 0.053-0.995, P=0.049) were the relevant factors of the severe psychological distress before IMRT. Occupation (OR=2.286, 95%CI 1.291-4.050, P=0.005) and medical insurance (OR=0.089, 95%CI 0.029-0.276, P<0.001) were the relevant factors of severe psychological distress after IMRT. Conclusion The incidence rate of distress is high in elderly patients with head and neck cancer before IMRT, which can be aggravated after IMRT, primarily the treatment-related physical pain problems.
Bao Ruizhi,Yi Junlin,Liu Qingfeng et al. Analysis of psychological distress in elderly patients with head and neck cancer receiving radiotherapy[J]. Chinese Journal of Radiation Oncology, 2021, 30(2): 109-113.
Bao Ruizhi,Yi Junlin,Liu Qingfeng et al. Analysis of psychological distress in elderly patients with head and neck cancer receiving radiotherapy[J]. Chinese Journal of Radiation Oncology, 2021, 30(2): 109-113.
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2021, Vol. 30 
