术前术后宫颈癌膀胱充盈度一致性在调强放疗中对靶区及危及器官重要性研究

doi:10.3760/cma.j.issn.1004-4221.2019.06.009

Abstract
Figure/Table
References()
Related Citation (15)
Read Tracking
Download Tracking

Download: PDF (0 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS) Supporting Info

Abstract Objective Bladder filling in patients with cervical cancer before and after operation during intensity-modulated radiotherapy (IMRT) was controlled by using bladder volume measurement instrument (BVI 9400). The displacement errors of the target area and the changes of the irradiation dose and the morphology of the filling bladder were compared. The significance of consistency of preoperative and postoperative bladder filling in IMRT for cervical cancer was investigated.Methods Forty-five patients with cervical cancer treated with radiotherapy in our hospital in 2018 were recruited and divided into A,B and C groups (n=15). In group A, patients did not undergo surgery, patients in group B received radical resection of cervical cancer (bladder volume measurement (BVI 9400) was utilized to monitor the bladder urine volume in both A and B groups before treatment). In group C, patients who self-controlled urination without monitoring bladder urine volume before treatment were randomly selected. All patients in three groups underwent KV-CBCT scan before treatment for online registration analysis. The displacement errors in the x-(left and right),y-(head and foot),z-axis directions (ventral and dorsal), PTV coverage volume percentage(V100) and percentage difference (ΔV100) of the prescription dose were calculated.Results The average displacement errors in the x-, y-, z-axis directions were as follows:1.67 mm,1.55 mm and 1.67 mm in group A, 1.43 mm,1.58 mm and 1.84 mm in group B, and 2.27 mm,2.30 mm and 2.08 mm in group C, respectively. In group A, the V100 was calculated as 96.96% and ΔV100 was 1.17%. In group B, V100 was95.9% and ΔV100 was 1.29%. In group C, V100 was 94.02% and ΔV100 was 2.17%.Conclusions Controlling the consistency of bladder filling can reduce the effect of inconsistency of bladder filling upon the displacement errors to certain extent, which can guarantee the accuracy of the target location and the irradiation dose of the target, protect the bladder, small intestine and rectum, and alleviate the radiation-induced response of cervical cancer patients.

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	Zhang Wei
	Xu Qing
	Ke Guihao
	Zhu Jun
	Guan Shikuo
	Zhang Yanjun

Key words： Bladder filling status Planning target volume Cervical neoplasm/intensity-modulated radiotherapy

Received: 14 November 2018

Corresponding Authors: Xu Qing, Email:396617183@qq.com

Cite this article:

Zhang Wei,Xu Qing,Ke Guihao et al. Study on the significance of consistency of preoperative and postoperative bladder filling in patients with cervical cancer for target area and organ at risk in IMRT[J]. Chinese Journal of Radiation Oncology, 2019, 28(6): 438-441.

URL:

http://journal12.magtechjournal.com/Jweb_fszlx/EN/10.3760/cma.j.issn.1004-4221.2019.06.009 OR http://journal12.magtechjournal.com/Jweb_fszlx/EN/Y2019/V28/I6/438

[1] 林原,周莉均,徐志勇,等.宫颈癌术后盆腔三维适形和与调强放疗计量学与技术的研究[J].中华放射肿瘤学杂志,2008,17(5):372-376.DOI:10.3321/j.issn:1004-4221.2008.05.011.
Lin Y,Zhou LJ,Xu ZY,et al. A study on the metrology and technique of three dimensional conformal and intensity modulated radiotherapy for cervical cancer after operation[J].Chin J Radiat Oncol,2008,17(5);372-376.DOI:10.3321/j.issn:1004-4221.2008.05.011.
[2] 庞皓文,邱杰,全红,等.宫颈癌调强放疗中膀胱解剖结构变化及对其吸收剂量影响研究[J].中华放射肿瘤学杂志,2011,20(3):218-221.DOI:10.3760/cma.j.issn.1004-4221.2011.03.014.
Pang HW,Qiu J,Quan H,et al. Study on the changes of bladder Anatomical structure and its effect on absorbed dose in intensity-modulated radiotherapy for cervical cancer[J].Chin J Radiat Oncol,2011,20(3):218-221.DOI:10.3760/cma.j.issn.1004-4221.2011.03.014.
[3] 付庆国,邓烨,杨海明,等.膀胱充盈度对宫颈癌术后放疗靶区照射剂量的影响[J].中国肿瘤临床与康复,2015,22(2):167-169.DOI:10.13455/j.cnki.cjcor.2015.02.13.
Fu GQ,Deng Y,Yang HM,et al. Effect of bladder filling on radiation dose of radiotherapy target after postoperative radiotherapy for cervical cancer[J]. Clin Rehabilitat Cancer China,2015,22(2):167-169.DOI:10.13455/j.cnki.cjcor.2015.02.13.
[4] 卢渊全.膀胱充盈状态对宫颈癌术后盆腔放疗影响的研究[J].中国临床实用医学,2009,3(5):7-9.DOI:10.3760/cma.j.issn 1673-8799.2009.05.03.
Lu YQ.Effect of bladder filling status on pelvic radiotherapy after cervical cancer surgery[J].Chin Clin Pract Med,2009,3(5):7-9.DOI:10.3760/cma.j.issn 1673-8799.2009.05.03.
[5] 刘跃平,刘新帆,李晔雄,等.三维适形放疗膀胱充盈状态对前列腺靶区和重要器官的影响[J].中华放射肿瘤学杂志,2007,16(1):48-51.DOI:10.3760/j.issn:1004-4221.2007.01.012.
Liu YP,Liu XF,Li YX,et al. Effect of bladder filling status on prostate target and important organs in three-dimensional conformal radiotherapy[J].Chin J Radiat Oncol,2007,16(1):48-51.DOI:10.3760/j.issn:1004-4221.2007.01.012.
[6] 吴丽华,王颖,靳富,等.便携式膀胱扫描仪在子宫颈癌放疗中的应用及其重要性[J].中国医学物理学杂志,2016,33(7):654-657.DOI:10.3969/j.issn.1005-202X.2016.07.002.
Wu LH,Wang Y,Jin F,et al. Application and importance of portable bladder scanner in cervical cancer radiotherapy[J].Chin J Med Phys,2016,33(7):654-657.DOI:10.3969/j.issn.1005-202X.2016.07.002.