[an error occurred while processing this directive] | [an error occurred while processing this directive]
Research of obtaining pseudo-CT images based on ultrasound deformation fields in radiotherapy
Sun Hongfei1,2,4,Guo Chang3,Lin Tao2,4,Gao Liugang2,4,Sui Jianfeng2,4,Xie Kai2,4,Ni Xinye2,4,He Xia3,4
1Nanjing Medical University,Nanjing 211166,China; 2Department of Radiation Oncology,Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University,Changzhou 213003,China; 3Department of Radiation Oncology,Affiliated Cancer Hospital of Nanjing Medical University,Nanjing 210009,China; 4Center for Medical Physics Nanjing Medical University, Nanjing 211166, China
Abstract Objective An improved method for obtaining pseudo-computed tomography (CTps) based on ultrasound deformation field. Methods The three-dimensional image data of computed tomography and ultrasound for three postoperative cervical cancer patients were selected,including the CT (CTsim) and ultrasound (USsim) images obtained during the simulated positioning stage,and the cone beam CT (CBCT) and ultrasound images obtained during the positioning verification stage of the treatment one week later. Binary masks of the OROI and OROW were created and applied in ultrasound image registration;thus,the deformation field was obtained. The deformation field was applied to CTsim images and different pseudo-CT images were obtained. Similarities between these pseudo-CT images and those of CBCT were compared,and registration accuracies between pseudo-CT images under different binary masks and CTsim were discussed. Results The averages of the correlation coefficient between pseudo-CT based on OROI,OROW,no binary mask and CBCT were 0.95,0.82 and 0.64 respectively. The average of the normalized mean square Error were 0.12,0.42 and 0.57 respectively. Conclusion The pseudo-CT based on OROI binary mask matches the best with CTsim and achieves the highest similarity with CBCT.
Corresponding Authors:
Ni Xinye,Email:nxy@njmu.edu.cn
Cite this article:
Sun Hongfei,Guo Chang,Lin Tao et al. Research of obtaining pseudo-CT images based on ultrasound deformation fields in radiotherapy[J]. Chinese Journal of Radiation Oncology, 2019, 28(4): 297-301.
Sun Hongfei,Guo Chang,Lin Tao et al. Research of obtaining pseudo-CT images based on ultrasound deformation fields in radiotherapy[J]. Chinese Journal of Radiation Oncology, 2019, 28(4): 297-301.
[1] Luxton G.Adaptive radiation therapy[J].Med Phys,2011,38(1):123-132.DOI:10.1088/0031-9155/42/1/008. [2] El-Gamal EZA,Elmogy M,Atwan A.Current trends in medical image registration and fusion[J].Egypt Informat J,2016,17(1):99-124.DOI:10.1016/j.eij.2015.09.002. [3] Pennec X,Cachier P,Ayache N.Tracking brain deformations in time-sequences of 3D US images[J].2001,24(4-5):801-813.DOI:10.1016/S0167-8655(02)00183-6. [4] van der Meer S,Camps SM,van Elmpt WJ,et al. Simulation of pseudo-CT images based on deformable image registration of ultrasound images:a proof of concept for transabdominal ultrasound imaging of the prostate during radiotherapy[J].Med Phys,2016,43(4):1913-1920.DOI:10.1118/1.4944064. [5] Camps S,van der Meer S,Verhaegen F,et al. Various approaches for pseudo-CT scan creation based on ultrasound to ultrasound deformable image registration between different treatment time points for radiotherapy treatment plan adaptation in prostate cancer patients[J].Biomed Phys Engineer Exp,2016,2(3):035018.DOI:10.1088/2057-1976/2/3/035018. [6] Senin N,Colosimo BM,Pacella M.Point set augmentation through fitting for enhanced ICP registration of point clouds in multisensor coordinate metrology[J].Robot Comput-Integrat Manufact,2013,29(29):39-52. DOI:10.1016/j.rcim.2012.07.003. [7] Robinson D,Liu D,Steciw S,et al. An evaluation of the Clarity 3D ultrasound system for prostate localization[J].J Appl Clin Med Phys,2012,13(4):100-112.DOI:10.1120/jacmp.v13i4.3753. [8] 相艳,贺建峰,张云春,等.基于交叉累计剩余熵的图像配准中插值方法的改进[J].计算机工程,2015,41(10):199-203.DOI:10.3969/j.issn.1000-3428.2015.10.037. Xiang Y,He JF,Zhang YC,et al. Improvement of interpolation method in image registration based on cross cumulative residual entropy[J].Comput Engineer,2015,41(10):199-203.DOI:10.3969/j.issn.1000-3428.2015.10.037. [9] Mvsr T,Kumar A,Prasanth CVS.Comparative analysis of windowing techniques in minimizing side lobes in an antenna array[A]// IEEE.International conference on communications and signal processing[C].2014.HangZhou:IEEE,2014:1380-1383. [10] 陆雪松.聚焦超声治疗系统中的图像非刚性配准算法研究及应用[D].上海交通大学,2008.Lu XS.Research and application of image non-rigid registration algorithm in focused ultrasound therapy system[D].Shanghai Jiaotong University,2008. [11] Shamonin adp,Bron EE,Lelieveldt BPF,et al. Fast parallel image registration on CPU and GPU for diagnostic classification of Alzheimer's disease[J].Front Neuroinformat,2013,7(50):50-60.DOI:10.3389/fninf.2013.00050. [12] Guo D,Shamai S,Verdu S.Mutual information and minimum mean-square error in Gaussian channels[J].IEEE Trans InformatTheory,2005,51(4):1261-1282.DOI:10.1109/TIT.2005.844072. [13] Kim J,Fessler J A.Intensity-based image registration using robust correlation coefficients[J].IEEE Trans Med Imag,2004,23(11):1430-1444.DOI:10.1109/TMI.2004.835313. [14] Yan H,Zhen X,CervioL,et al. Progressive cone beam CT dose control in image-guided radiation therapy[J].Med Phys,2013,40(6):060701.DOI:10.1118/1.4804215. [15] Fargier-Voiron M,Presles B,Pommier P,et al. Ultrasound versus Cone-beam CT image-guided radiotherapy for prostate and post-prostatectomy pretreatment localization[J].Phys Med,2015,31(8):997-1004.DOI:10.1016/j.ejmp.2015.07.147. [16] Hai N,Hou Q,Ding X,et al. Ultrasound-guided transcervical radiofrequency ablation forsymptomatic uterine adenomyosis[J].Br J Radiol,2016,90(1069):20160119.DOI:10.1259/bjr.20160119. [17] Baron TH,Grimm IS,Gerber DA.Liver transplantation after endoscopic ultrasound–guided cholecystoduodenostomy for acute cholecystitis:A note of caution[J].Liver Transplant,2015,21(10):1322-1323.DOI:10.1002/lt.24168. [18] Nesvacil N,Schmid MP,Ptter R,et al. Combining transrectal ultrasound and CT for image-guided adaptive brachytherapy of cervical cancer:Proof of concept.[J].Brachytherapy,2016,15(6):1-6.DOI:10.1016/j.brachy.2016.08.009. [19] Li M,Ballhausen H,Hegemann NS,et al. A comparative assessment of prostate positioning guided by three-dimensional ultrasound and cone beam CT[J].Radiat Oncol,2015,10(1):82-83.DOI:10.1186/s13014-015-0380-1.
2019, Vol. 28 
